Blood Transfusions in Thalassemia Patients, Complications and Adverse Effects
|ClinicalTrials.gov Identifier: NCT00971880|
Recruitment Status : Completed
First Posted : September 4, 2009
Last Update Posted : August 26, 2011
Patients suffering from Thalassemia or another hemoglobinopathies required regular blood transfusions. The complications and adverse effects of blood transfusions can be classified as immediate and late. Among the immediate effects the most common are allergic reactions and fever, besides congestive heart failure in patients with cardiomyopathy. The late effects are mostly related to blood transmitted infections like HIV or Hepatitis C infections.
The purpose of this study is to summarize the data of those complications in a cohort of 100 patients receiving regular blood transfusion.
|Condition or disease||Intervention/treatment|
|Thalassemia Sickle Cell Anemia||Other: Clinical medical record summary|
About 100 patients aged several months to 50 years are treated in the Pediatric Hematology Unit, most of those patients receive blood transfusions monthly. The adverse reactions were routinely recorded during each transfusion. All the patients were also screened annually for the incidence of blood transmitted infections principally HIV and Hepatitis C. All those records will be systematically screened and all the immediate or late adverse reactions and complications related to blood transfusions will be summarized.
A second goal of this study will be to control the staff strictness related to the ministry of health protocol dealing to blood transfusions.
|Study Type :||Observational|
|Estimated Enrollment :||100 participants|
|Official Title:||Blood Transfusions in Thalassemia Patients, Complications and Adverse Effects.|
|Study Start Date :||May 2009|
|Actual Primary Completion Date :||November 2010|
|Actual Study Completion Date :||November 2010|
Patients receiving blood transfusions
All the patients with blood disorders that require blood transfusions
Other: Clinical medical record summary
Summary of immediate and late adverse effects of blood transfusions
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00971880
|Pediatric Hematology Unit and Pediatric Dpt B - HaEmek Medical Center|
|Afula, Israel, 18101|