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Connecting the Lab to Everyday Life: The Relevance of Executive Dysfunction to Participation and Quality of Life in Parkinson's Disease (PD) Without Dementia (Lab2Life)

This study has been completed.
Sponsor:
Information provided by (Responsible Party):
Erin Foster, Washington University School of Medicine
ClinicalTrials.gov Identifier:
NCT00917280
First received: June 8, 2009
Last updated: June 1, 2015
Last verified: June 2015
  Purpose
The overall purpose of this research is to learn how Parkinson's disease affects thinking and memory in everyday life. Participation will involve thinking tests, questionnaires and interviews about thinking and activities in everyday life.

Condition
Parkinson's Disease

Study Type: Observational
Study Design: Observational Model: Case Control
Time Perspective: Cross-Sectional
Official Title: Connecting the Lab to Everyday Life: The Relevance of Executive Dysfunction to Participation and Quality of Life in PD Without Dementia

Resource links provided by NLM:


Further study details as provided by Erin Foster, Washington University School of Medicine:

Enrollment: 174
Study Start Date: December 2008
Study Completion Date: July 2014
Primary Completion Date: July 2014 (Final data collection date for primary outcome measure)
Groups/Cohorts
Parkinson's Disease
Parkinson Disease participants without dementia
Control
Non-PD participants, matched for age, education and gender.

Detailed Description:
The overall purpose of this research is to learn how Parkinson's disease affects thinking and memory in everyday life. Participation will involve thinking tests, questionnaires and interviews about thinking and activities in everyday life.
  Eligibility

Ages Eligible for Study:   40 Years to 70 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population

Controls:

Recruited from community, VFH.

Criteria

Inclusion Criteria PD participants:

  • WUSM Movement Disorders Clinic patients
  • males or females between 40 and 70
  • meet criteria for idiopathic typical PD
  • classified at Hoehn & Yahr12 stage I, II, or III
  • are currently treated with levodopa/carbidopa

Inclusion Criteria Control:

  • The groups will be matched for age, education and gender
  • No Parkinson Disease

Exclusion Criteria PD participants and Control:

  • suspected dementia
  • treatment with certain dopaminergic, anticholinergic or benzodiazepine medications
  • other neurological problems
  • brain surgery
  • history or current psychotic disorder
  • any condition which would interfere with testing
  • control only: a biological family history of PD and being a caregiver or spouse of someone who has PD
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00917280

Locations
United States, Missouri
Washington University School of Medicine
St. Louis, Missouri, United States, 63110
Sponsors and Collaborators
Washington University School of Medicine
Investigators
Principal Investigator: Erin Foster Washington University School of Medicine
  More Information

Responsible Party: Erin Foster, Assistant Professor of Occupational Therapy, Neurology and Psychiatry, Washington University School of Medicine
ClinicalTrials.gov Identifier: NCT00917280     History of Changes
Other Study ID Numbers: #E07-117
Study First Received: June 8, 2009
Last Updated: June 1, 2015

Keywords provided by Erin Foster, Washington University School of Medicine:
Parkinson's Disease

Additional relevant MeSH terms:
Parkinson Disease
Dementia
Parkinsonian Disorders
Basal Ganglia Diseases
Brain Diseases
Central Nervous System Diseases
Nervous System Diseases
Movement Disorders
Neurodegenerative Diseases
Neurocognitive Disorders
Mental Disorders

ClinicalTrials.gov processed this record on June 28, 2017