Natural History of Autoimmune Diabetes and Its Complications
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|ClinicalTrials.gov Identifier: NCT00896610|
Recruitment Status : Recruiting
First Posted : May 11, 2009
Last Update Posted : March 29, 2018
- Diabetes is a disease defined by abnormally high blood sugar (glucose) levels. Glucose is an essential source of energy for the body s cells, but insulin is required to move the glucose into the cells. Insulin is a hormone produced by the pancreas that allows glucose to enter cells.
- In diabetes, the body is unable to supply enough insulin to meet its demands. The problem may be a low supply of insulin or a high demand for insulin. Someone who has been diagnosed with diabetes has lost much of their insulin-producing capacity. Clinical studies have shown that good control of blood sugar is essential to prevent diabetes complications like damage to the eyes, kidneys, nerves, and blood vessels.
- To establish a relationship with several individuals with diabetes caused by the immune system attacking the body s insulin-producing cells in order to:
- Explore why the immune system attacks insulin-producing cells.
- Understand why some individuals develop diabetes-related complications and others do not.
- Develop therapies to improve how patients can control their blood sugar levels.
- Continue to follow subjects who have completed or are considering other NIH diabetes-related studies.
- To develop improved tests for determining an individual s risk for developing diabetes and/or to accurately diagnose the exact type of diabetes.
- Individuals who have been diagnosed with or are at risk for developing diabetes.
- Standard physical examination and clinical tests to determine if the patient has diabetes or to confirm a particular type of diabetes:
- None of the treatment in this study is experimental.
- Patients will receive a separate consent form for any special tests needed to learn more about their particular type of diabetes.
- Patients may be asked to provide additional urine and blood samples for use in laboratory research about diabetes.
- Researchers may offer medical treatment advice for diabetes, or explain how to improve patients diabetes management skills.
|Condition or disease|
|Type 1 Diabetes Type 2 Diabetes Immunologically Mediated Type 1 Diabetes Anti Beta-Cell Autoantibodies Autoimmunity|
|Study Type :||Observational|
|Estimated Enrollment :||99999999 participants|
|Official Title:||Natural History of Autoimmune Diabetes and Its Complications|
|Study Start Date :||May 4, 2009|
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00896610
|Contact: Craig S Cochran, R.N.||(301) firstname.lastname@example.org|
|Contact: Ranganath Muniyappa, M.D.||(301) email@example.com|
|United States, Maryland|
|National Institutes of Health Clinical Center, 9000 Rockville Pike||Recruiting|
|Bethesda, Maryland, United States, 20892|
|Contact: For more information at the NIH Clinical Center contact Office of Patient Recruitment (OPR) 800-411-1222 ext TTY8664111010 firstname.lastname@example.org|
|Principal Investigator:||Ranganath Muniyappa, M.D.||National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)|