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Discard:Characterisation of Colonic Polyps in Vivo (DISCARD)

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ClinicalTrials.gov Identifier: NCT00888771
Recruitment Status : Completed
First Posted : April 28, 2009
Last Update Posted : February 12, 2016
Sponsor:
Information provided by (Responsible Party):
Imperial College London

Brief Summary:
Prospective study of accuracy of colonic polyp characterisation in vivo using high resolution white light endoscopy, narrow band imaging and chromoendoscopy.

Condition or disease
Colorectal Polyps

Study Type : Observational
Actual Enrollment : 130 participants
Observational Model: Cohort
Time Perspective: Prospective
Official Title: Characterisation of Small Colonic Polyps in Vivo
Study Start Date : August 2008
Actual Primary Completion Date : February 2009
Actual Study Completion Date : June 2009

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Colonic Polyps

Group/Cohort
1
2
3
4



Primary Outcome Measures :
  1. Accuracy of polyp characterisation [ Time Frame: 12 months ]

Secondary Outcome Measures :
  1. Change in surveillance interval after formal histopathology [ Time Frame: 12 months ]


Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years and older   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
The study group therefore would comprise those presenting for 3 yearly follow up or sooner i.e. those with a resected colorectal cancer or those with ≥ three adenomas or one advanced ≥10mm adenoma or those with a positive faecal occult blood test
Criteria

Inclusion Criteria:

  1. Patients over 18 years of age, assessed as fit for routine colonoscopy
  2. Patients attending for screening or surveillance colonoscopy meeting the following criteria:

    • Polyp surveillance with at least 3 adenomas or 1 adenoma>10mm at previous colonoscopy
    • Surveillance post colorectal cancer resection
    • Screening with positive faecal occult blood test

Exclusion Criteria:

  1. Patients with known colitis or polyposis syndromes
  2. Unable or unwilling to give informed consent

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00888771


Locations
United Kingdom
Wolfson Unit for Endoscopy, St Mark's Hospital
Harrow, Moddlesex, United Kingdom, HA1 3UJ
Sponsors and Collaborators
Imperial College London
Investigators
Principal Investigator: Brian P Saunders, MD Wolfson Unit for Endoscopy, St Mark's Hospital

Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
Responsible Party: Imperial College London
ClinicalTrials.gov Identifier: NCT00888771     History of Changes
Other Study ID Numbers: 05/Q0405/121/1
First Posted: April 28, 2009    Key Record Dates
Last Update Posted: February 12, 2016
Last Verified: July 2010

Keywords provided by Imperial College London:
Colorectal cancer
polyps
colonoscopy
advanced imaging

Additional relevant MeSH terms:
Polyps
Colonic Polyps
Pathological Conditions, Anatomical
Intestinal Polyps