Telephone Cognitive-Behavioral Therapy (CBT) for Subthreshold Depression and Presenteeism in Workplace
![]() |
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. |
ClinicalTrials.gov Identifier: NCT00885014 |
Recruitment Status :
Completed
First Posted : April 21, 2009
Last Update Posted : March 19, 2012
|
- Study Details
- Tabular View
- Results Submitted
- Disclaimer
- How to Read a Study Record
Condition or disease | Intervention/treatment | Phase |
---|---|---|
Depression | Behavioral: CBT Behavioral: EAP | Phase 2 Phase 3 |
Study Type : | Interventional (Clinical Trial) |
Actual Enrollment : | 118 participants |
Allocation: | Randomized |
Intervention Model: | Parallel Assignment |
Masking: | None (Open Label) |
Primary Purpose: | Treatment |
Official Title: | Telephone Cognitive-behavioral Therapy for Subthreshold Depression and Presenteeism in Workplace: a Randomized Controlled Trial |
Study Start Date : | April 2009 |
Actual Primary Completion Date : | April 2011 |
Actual Study Completion Date : | September 2011 |

Arm | Intervention/treatment |
---|---|
Experimental: CBT
Telephone cognitive-behavioral therapy
|
Behavioral: CBT
Telephone cognitive-behavioral therapy Behavioral: EAP Employees Assistance Program |
Active Comparator: TAU
Treatment as usual through the Employees Assistance Program
|
Behavioral: EAP
Employees Assistance Program |
- Depression severity as measured by Beck Depression Inventory-II (BDI2) [ Time Frame: 4 months post-randomization ]
- Work performance as measured by the Health and Work Performance Questionnaire (HPQ) "effective hours worked" for the past month [ Time Frame: 4 months post-randomization ]
- Depression severity as measured by Kessler Scale (K6) [ Time Frame: 4 months post-randomization ]
- Client satisfaction as measured by Visual Analogue Scale (VAS) [ Time Frame: 4 months post-randomization ]
- Depression severity as measured by BDI2 and K6 [ Time Frame: 15 months post-randomization ]
- Work performance as measured by HPQ and by job retention [ Time Frame: 15 months post-randomization ]
- Client satisfaction as measured by VAS [ Time Frame: 15 months post-randomization ]
- Use of EAP services and other health services [ Time Frame: 15 months post-randomization ]
- Suicidal attempt and/or hospitalization (physical or mental) [ Time Frame: 15 months post-randomization ]
- Time to incident major or minor depressive episode [ Time Frame: 15 months post-randomization ]

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.
Ages Eligible for Study: | 20 Years to 57 Years (Adult) |
Sexes Eligible for Study: | All |
Accepts Healthy Volunteers: | No |
Inclusion Criteria:
- Age 20-57 at study entry [because the retirement age is usually 60, we have to recruit the patients well before 60 in order to allow time for follow-up]
- Men and women
- Currently employed full-time (either regular or temporary) by the business company
- Expected to be employed full-time for 2 years after screening
- K6 scores greater than or equal to 9 (or 10) at screening
- BDI2 scores greater than or equal to 10 at 2nd screening (Composite International Diagnostic Interview (CIDI) interview)
Exclusion Criteria:
- Part-time employees
- Sick leave for 6 or more days for a physical or mental condition in the past month
- Expected to be on pregnancy leave, maternity leave or nursing leave within 2 years after screening
- Current treatment for a mental health problem from a mental health professional
- Major depressive episode in the past month, as ascertained by CIDI [We do not exclude dysthymia or major depression in partial remission]
- Lifetime history of bipolar disorder, as ascertained by CIDI
- Any substance dependence in the past 12 months, as ascertained by CIDI. [We do not exclude substance abuse.]
- Any other current mental disorder if it constitutes the predominant aspect of the clinical presentation and requires treatment not offered in the project
- Those who have already received the telephone CBT in the pilot runs

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00885014
Japan | |
Nagoya City University | |
Nagoya, Aichi, Japan, 467-8601 |
Principal Investigator: | Toshiaki Furukawa, MD, PhD | Nagoya City University |
Responsible Party: | Toshiaki A. Furukawa, Professor, Kyoto University |
ClinicalTrials.gov Identifier: | NCT00885014 |
Other Study ID Numbers: |
NCUPsychiatry002 |
First Posted: | April 21, 2009 Key Record Dates |
Last Update Posted: | March 19, 2012 |
Last Verified: | March 2012 |
Depressive disorder Behavior therapy Workplace Subthreshold depression |
Depression Depressive Disorder Behavioral Symptoms Mood Disorders Mental Disorders |