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Exercise During Chemotherapy for Patients With Hematological Malignancies

The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified December 2009 by Charite University, Berlin, Germany.
Recruitment status was:  Recruiting
Information provided by:
Charite University, Berlin, Germany Identifier:
First received: April 17, 2009
Last updated: December 21, 2009
Last verified: December 2009
The trial will evaluate the effects of aerobic exercise in patients undergoing chemotherapy for the treatment of a hematological neoplastic disease.

Condition Intervention Phase
Hematological Diseases Hematological Malignancies Other: Aerobic exercise Behavioral: Fatigue counseling Phase 3

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single (Investigator)
Official Title: Exercise During Chemotherapy for Patients With Hematological Malignancies

Resource links provided by NLM:

Further study details as provided by Charite University, Berlin, Germany:

Primary Outcome Measures:
  • Fatigue [ Time Frame: At recruitment and after 12 weeks ]

Secondary Outcome Measures:
  • Complications [ Time Frame: At recruitment and after 12 weeks ]
  • Physical performance [ Time Frame: At recruitment and after 12 weeks ]

Estimated Enrollment: 60
Study Start Date: May 2009
Estimated Study Completion Date: September 2011
Estimated Primary Completion Date: April 2011 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Active Comparator: Control Behavioral: Fatigue counseling
The patients will receive a counseling regarding the causes of fatigue, how to cope with this symptom, and general recommendations about exercise. However, they will not participate at a structured exercise program.
Experimental: Exercise Other: Aerobic exercise
The patients will carry out an aerobic exercise program consisting of walking on a treadmill for 30 minutes at an intensity of 80% of the maximum heart rate. The training will be carried out three times a week.


Ages Eligible for Study:   18 Years to 70 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • Hematological malignant disease
  • Current chemotherapy
  • Understanding of written German

Exclusion Criteria:

  • Cardiorespiratory, metabolical, osteoarticular or immunological disorders which can be aggravated by exercise
  • Pathological stress-ECG at recruitment
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT00884364

Contact: Fernando Dimeo, MD +493084452098

Section Sports Medicine, Charité Universitätsmedizin Berlin, Hindenburgdamm 30 Recruiting
Berlin, Germany, 12200
Contact: Fernando Dimeo, MD         
Principal Investigator: Fernando Dimeo, MD         
Sponsors and Collaborators
Charite University, Berlin, Germany
Principal Investigator: Fernando Dimeo, MD Charite University, Berlin, Germany
  More Information

Responsible Party: Dr. Fernando Dimeo, Dept. of Sports Medicine, Charité Universitätsmedizin Berlin Identifier: NCT00884364     History of Changes
Other Study ID Numbers: EA4/031/09
Study First Received: April 17, 2009
Last Updated: December 21, 2009

Keywords provided by Charite University, Berlin, Germany:
Multiple myeloma
Hodgkin´s disease
Hematological neoplastic diseases

Additional relevant MeSH terms:
Hematologic Diseases processed this record on September 21, 2017