Assessment of Colonic Permeability by Confocal Laser Endomicroscopy
|ClinicalTrials.gov Identifier: NCT00883077|
Recruitment Status : Unknown
Verified October 2009 by Shandong University.
Recruitment status was: Recruiting
First Posted : April 17, 2009
Last Update Posted : October 14, 2009
|Condition or disease|
|Inflammatory Bowel Disease Ulcerative Colitis Irritable Bowel Syndrome|
|Study Type :||Observational|
|Estimated Enrollment :||30 participants|
|Observational Model:||Case Control|
|Official Title:||Combined Assessment of Colonic Permeability by Real Time Confocal Laser Endomicroscopy and Sucralose Absorption Test|
|Study Start Date :||April 2009|
|Estimated Primary Completion Date :||November 2009|
|Estimated Study Completion Date :||December 2009|
Patients with long standing history or short onset of ulcerative colitis.
Asymptomatic individuals admitted for health surveillance or patients for follow up after polypectomy.
Irritable bowel syndrome
Patients admitted to outpatient department with symptoms meeting ROME III criteria of irritable bowel syndrome.
- Fluorescein leakage under confocal laser endomicroscopy observation of colonic mucosa. [ Time Frame: Within the 30 minutes after injection of fluorescein ]
- Total sucralose excretion. [ Time Frame: Within the 24 hours after drinking of sucralose ]
Biospecimen Retention: Samples With DNA
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00883077
|Contact: Yanqing Li, PhD. MD.||86-531-8216923 ext firstname.lastname@example.org|
|Department of Gastroenterology, Qilu Hospital, Shandong University||Recruiting|
|Jinan, Shandong, China, 250012|
|Contact: Yanqing Li, PhD. MD. 86-531-82169236 ext 82169508 email@example.com|
|Principal Investigator: Yanqing Li, PhD. MD.|
|Sub-Investigator: Changqing Li, PhD.|
|Study Director:||Yanqing Li, PhD. MD.||Department of Gastroenterology, Qilu Hospital, Shandong University|