Long-Standing Persistant Atrial Fibrillation-Pulmonary Vein Isolation With or Without Ablation (Alster-Lost)
![]() |
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. |
ClinicalTrials.gov Identifier: NCT00820625 |
Recruitment Status :
Completed
First Posted : January 12, 2009
Last Update Posted : February 8, 2017
|
- Study Details
- Tabular View
- No Results Posted
- Disclaimer
- How to Read a Study Record
Condition or disease | Intervention/treatment | Phase |
---|---|---|
Atrial Fibrillation Tachycardia | Procedure: pulmonary vein isolation Procedure: pulmonary vein isolation with additional ablation of fragmented potentials | Not Applicable |
Study Type : | Interventional (Clinical Trial) |
Actual Enrollment : | 124 participants |
Allocation: | Randomized |
Intervention Model: | Parallel Assignment |
Masking: | Single (Participant) |
Primary Purpose: | Treatment |
Official Title: | Ablation at St. Georg Hospital for Long-Standing Persistent Atrial Fibrillation - Pulmonary Vein Isolation With or Without Ablation of Complex Fragmented Atrial Potentials |
Study Start Date : | May 2008 |
Actual Primary Completion Date : | February 2017 |
Actual Study Completion Date : | February 2017 |

Arm | Intervention/treatment |
---|---|
Active Comparator: 1
ablation: pulmonary vein isolation
|
Procedure: pulmonary vein isolation
common pulmonary vein isolation procedure |
Active Comparator: 2
ablation: pulmonary vein isolation with additional ablation of fragmented potentials
|
Procedure: pulmonary vein isolation with additional ablation of fragmented potentials
common pulmonary vein isolation with additional but also common ablation of fragmented potentials |
- data collection in view of acute and chronic success rate [ Time Frame: 12 months ]
- data collection of complications in both groups and also procedure parameters [ Time Frame: 12 months ]

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.
Ages Eligible for Study: | 18 Years to 75 Years (Adult, Older Adult) |
Sexes Eligible for Study: | All |
Accepts Healthy Volunteers: | No |
Inclusion Criteria:
- long standing persistent atrial fibrillation > 6 months and < 5 years
Exclusion Criteria:
- renal failure
- left atrial size >55 mm

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00820625
Germany | |
Asklepios Klinik St. Georg | |
Hamburg, Germany |
Principal Investigator: | Karl-Heinz Kuck, PhD, MD | Asklepios Klinik St. Georg, Department of Cardiology |
Responsible Party: | Asklepios proresearch |
ClinicalTrials.gov Identifier: | NCT00820625 |
Other Study ID Numbers: |
1787 PV 2961 ( Other Identifier: Ethical Board Hamburg ) |
First Posted: | January 12, 2009 Key Record Dates |
Last Update Posted: | February 8, 2017 |
Last Verified: | February 2017 |
Individual Participant Data (IPD) Sharing Statement: | |
Plan to Share IPD: | Undecided |
Atrial Fibrillation Tachycardia Arrhythmias, Cardiac Heart Diseases |
Cardiovascular Diseases Pathologic Processes Cardiac Conduction System Disease |