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Sleep Disturbances as a Non-Traditional Risk Factor in Chronic Kidney Disease- University of Illinois (CRIC)

This study has been completed.
University of Illinois at Chicago
Information provided by (Responsible Party):
University of Chicago Identifier:
First received: January 5, 2009
Last updated: September 4, 2013
Last verified: September 2013
This study will help determine the relationship between impaired sleep and chronic kidney disease, specifically to determine if sleep disturbances are a risk factor for worsening kidney function.

Chronic Kidney Disease

Study Type: Observational
Study Design: Observational Model: Case Control
Time Perspective: Prospective
Official Title: Sleep Disturbances as a Non-Traditional Risk Factor in Chronic Kidney Disease

Resource links provided by NLM:

Further study details as provided by University of Chicago:

Primary Outcome Measures:
  • Sleep Quality [ Time Frame: Sleep Quality was determined after PSG on all subjects were completed ]

Enrollment: 89
Study Start Date: July 2006
Study Completion Date: June 2011
Primary Completion Date: June 2011 (Final data collection date for primary outcome measure)
Subjects with mild to moderate kidney disease
Healthy Control Subjects


Ages Eligible for Study:   21 Years to 74 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
Renal Clinic patients at The University of Illinois at Chicago Hospital

Inclusion Criteria:

  • CKD subjects will be participants in a larger study, CRIC, at the University of Illinois, Chicago
  • 30 Healthy controls age and gender matched to 30 CKD subjects, regular bedtimes of at least 6h/night, sedentary lifestyle

Exclusion Criteria:

  • Diabetes
  • Current or previous dialysis for more than 1 month
  • Uncontrolled hypertension
  • Heart failure
  • Liver disease
  • HIV
  • Hemoglobin < 10.5 g/dl
  • Treatment with EProcrit, Epogen, or Aranesp
  • Bone or organ transplant,
  • Use of immunosuppressive drugs within past 6 months
  • Current oral contraceptive use
  • Current pregnancy
  • Chemotherapy for malignancy within past 2 years
  Contacts and Locations
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Please refer to this study by its identifier: NCT00817492

United States, Illinois
The University of Illinois at Chicago
Chicago, Illinois, United States
Sponsors and Collaborators
University of Chicago
University of Illinois at Chicago
Principal Investigator: Eve Van Cauter, PhD University of Chicago
Principal Investigator: James Lash, MD University of Illinois at Chicago
  More Information

Responsible Party: University of Chicago Identifier: NCT00817492     History of Changes
Other Study ID Numbers: #14747A
5R01DK071696 ( US NIH Grant/Contract Award Number )
Study First Received: January 5, 2009
Last Updated: September 4, 2013

Keywords provided by University of Chicago:
Decreased sleep time
Decreased sleep quality

Additional relevant MeSH terms:
Kidney Diseases
Renal Insufficiency, Chronic
Sleep Wake Disorders
Urologic Diseases
Renal Insufficiency
Nervous System Diseases
Mental Disorders
Neurologic Manifestations
Signs and Symptoms processed this record on April 28, 2017