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Sleep at 30 Degrees in Glaucoma

This study has been completed.
Information provided by:
University Health Network, Toronto Identifier:
First received: December 2, 2008
Last updated: December 3, 2008
Last verified: December 2008

This study is designed to investigate the effect of body posture (particularly when sleeping) on the pressure in the eye. The effect of body posture on progressive glaucoma (glaucoma where a significant change i.e. a disc hemorrhage has occurred) is not known.

The study will involve being admitted to the Sleep Unit of the University Health Network at Toronto Western Hospital for 1 night (14 hours). IOP will be measured in both eyes every 2 hours with a Tonopen, along with brachial blood pressure (BP), in the sitting position until the patients reach their normal sleep cycle time. Patients will then be asked to sleep in either lying down or reclining at a 30 degrees position and have the IOP measurements and brachial BP every 2 hours in that position.

The same cohort of patients will then be invited for a repeat 14 hour IOP and BP measurement but will change their position, i.e. sitting before will now be supine and vice versa.

Condition Intervention
Glaucoma Behavioral: Sleeping position in glaucoma patient

Study Type: Interventional

Resource links provided by NLM:

Further study details as provided by University Health Network, Toronto:


Ages Eligible for Study:   40 Years to 80 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • This pilot study included patients with progressive NTG or POAG as evidenced by disc hemorrhage despite well controlled Intraocular pressures (IOP), who were able to sleep flat

Exclusion Criteria:

  • Any patients who were not able to sign a consent or lying flat during sleep
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT00802061

Canada, Ontario
Toronto Western Hospital
Toronto, Ontario, Canada, M5T 2S8
Sponsors and Collaborators
University Health Network, Toronto
  More Information Identifier: NCT00802061     History of Changes
Other Study ID Numbers: Trope 003
Study First Received: December 2, 2008
Last Updated: December 3, 2008

Keywords provided by University Health Network, Toronto:
progressive glaucoma despite controlled IOP

Additional relevant MeSH terms:
Ocular Hypertension
Eye Diseases processed this record on August 18, 2017