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Magnetic Resonance Imaging Follow-up on Temporomandibular Arthritis in Children With Juvenile Idiopathic Arthritis

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ClinicalTrials.gov Identifier: NCT00801593
Recruitment Status : Unknown
Verified December 2008 by University Hospital Tuebingen.
Recruitment status was:  Recruiting
First Posted : December 3, 2008
Last Update Posted : December 3, 2008
Sponsor:
Information provided by:

Study Description
Brief Summary:

Children with juvenile idiopathic arthritis (JIA) suffer in up to 87% of the cases of arthritis of the temporomandibular joints (TMJs). Magnetic resonance imaging (MRI) is the only modality for the early diagnosis of TMJ involvement.

Aim of the study is to compare symptoms and clinical findings with MRI and ultrasonography results and to describe the action of the current medication on the arthritis of the TMJs.


Condition or disease Intervention/treatment
Juvenile Idiopathic Arthritis Procedure: Steroid injection into the TMJs.

Study Design

Study Type : Observational
Estimated Enrollment : 50 participants
Observational Model: Cohort
Time Perspective: Prospective
Official Title: Arthritis of the Temporomandibular Joints in Children With Juvenile Idiopathic Arthritis- Pilot Study on Diagnostic Value of Ultrasonography and Magnetic Resonance Imaging and Influence of Drug Treatment
Study Start Date : May 2008
Estimated Primary Completion Date : December 2009
Estimated Study Completion Date : June 2010

Resource links provided by the National Library of Medicine

U.S. FDA Resources

Groups and Cohorts

Group/Cohort Intervention/treatment
Children with JIA Procedure: Steroid injection into the TMJs.
In case of otherwise noncontrollable TMJ involvement steroids are injected into arthritic TMJs under MRI guidance.


Outcome Measures

Primary Outcome Measures :
  1. TMJ arthritis on MRI [ Time Frame: every three to six months from recruitment to end of study ]

Secondary Outcome Measures :
  1. TMJ arthritis on ultrasound [ Time Frame: every three to six months from recruitment to end of study ]
  2. Action of current medication on TMJ arthritis. [ Time Frame: every three to six months from recruitment to end of study ]

Eligibility Criteria

Information from the National Library of Medicine

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Ages Eligible for Study:   7 Years to 17 Years   (Child)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population
Children with JIA.
Criteria

Inclusion Criteria:

  • Children with defined JIA.

Exclusion Criteria:

  • Children without defined diagnosis of JIA.
Contacts and Locations

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00801593


Contacts
Contact: Nikolay Tzaribachev, MD +49707129 ext 84711 nikolay.tzaribachev@med.uni-tuebingen.de

Locations
Germany
University Children's Hospital Recruiting
Tuebingen, Baden-Wuerttemberg, Germany, 72076
Contact: Nikolay Tzaribachev, MD    +49707129 ext 84711    nikolay.tzaribachev@med.uni-tuebingen.de   
Principal Investigator: Nikolay Tzaribachev, MD         
Sponsors and Collaborators
University Hospital Tuebingen
Investigators
Principal Investigator: Nikolay Tzaribachev, MD University Hospital Tuebingen
More Information

Responsible Party: Nikolay Tzaribachev, Dr., University Children's Hospital, Tuebingen
ClinicalTrials.gov Identifier: NCT00801593     History of Changes
Other Study ID Numbers: TMJ PROSPECT2008
First Posted: December 3, 2008    Key Record Dates
Last Update Posted: December 3, 2008
Last Verified: December 2008

Keywords provided by University Hospital Tuebingen:
JIA

Additional relevant MeSH terms:
Arthritis
Arthritis, Juvenile
Joint Diseases
Musculoskeletal Diseases
Rheumatic Diseases
Connective Tissue Diseases
Autoimmune Diseases
Immune System Diseases