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The Effects of Potassium on Physiological and Cardiovascular Variables in Healthy Persons

This study has been completed.
Information provided by (Responsible Party):
Erling Bjerregaard Pedersen, Regional Hospital Holstebro Identifier:
First received: December 2, 2008
Last updated: August 19, 2015
Last verified: December 2011
In humans living of fruit and vegetables, hypertension is rarely seen. We wish to study if the development of hypertension has a connection to our intake of potassium. We know that fruit and vegetables contain a lot of potassium and we will simulate this intake by giving healthy subjects potassium as tablets.

Condition Intervention Phase
Drug: Calcium
Drug: Potassium
Phase 1

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: Open Label
Primary Purpose: Treatment
Official Title: The Effects of Potassium on Physiological Variables in the Kidney and Cardiovascular Variables in Healthy Persons in a Double-blinded, Randomised, Placebo-controlled, Cross-over Study

Resource links provided by NLM:

Further study details as provided by Regional Hospital Holstebro:

Primary Outcome Measures:
  • Effect on blood pressure [ Time Frame: three months ]

Enrollment: 25
Study Start Date: November 2008
Study Completion Date: November 2011
Primary Completion Date: November 2011 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Placebo Comparator: 1
Calcium tablets
Drug: Calcium
tablets, 1 tablet 2 times per day in 28 days
Active Comparator: 2
Potassium tablets
Drug: Potassium
Tablets, 5 tablets 2 times per day for 28 days


Ages Eligible for Study:   18 Years to 40 Years   (Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes

Inclusion Criteria:

  • healthy
  • age 18-40 years old
  • BMI 18, 5-30
  • non-smoker

Exclusion Criteria:

  • daily use of medicine
  • alcohol or drugs
  • desire to become pregnant
  • not using safe anti-contraceptive
  • abnormal results in the initial testing
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Please refer to this study by its identifier: NCT00801034

Department of medical research
Holstebro, Denmark, 7500
Sponsors and Collaborators
Erling Bjerregaard Pedersen
  More Information

Publications automatically indexed to this study by Identifier (NCT Number):
Responsible Party: Erling Bjerregaard Pedersen, professor, chief physician, Regional Hospital Holstebro Identifier: NCT00801034     History of Changes
Other Study ID Numbers: MED.RES.HOS.2008.01.SKM
Study First Received: December 2, 2008
Last Updated: August 19, 2015

Keywords provided by Regional Hospital Holstebro:
blood pressure

Additional relevant MeSH terms:
Vascular Diseases
Cardiovascular Diseases processed this record on May 22, 2017