Laparoscopic Prostatectomy for Chronic Prostatitis

The recruitment status of this study is unknown because the information has not been verified recently.
Verified April 2011 by The Krongrad Institute.
Recruitment status was  Recruiting
Information provided by:
The Krongrad Institute Identifier:
First received: October 17, 2008
Last updated: April 29, 2011
Last verified: April 2011

Prostatitis is an inflammation of the prostate, an pelvic organ of men. Prostatitis can cause great discomfort which varies but can include pelvic pain, pelvic pressure, a vague sense of discomfort, a feeling of malaise and fatigue, fever, burning on urination, pain on reaching orgasm, and bleeding.

In many men the symptoms of prostatitis can be chronic. It is estimated that in the United States chronic prostatitis is responsible for as many as two million doctor visits a year. The disease can be ruinous, interfering with work, intimacy, and other things.

The causes of chronic prostatitis are not understood. The treatments commonly used, including antibiotics and prostate massage, work poorly. We now have evidence that laparoscopic prostatectomy can eliminate the misery of chronic prostatitis. This trial aims to quantify and better characterize the effect of laparoscopic prostatectomy on the symptoms of chronic prostatitis.

Condition Intervention Phase
Chronic Prostatitis With Chronic Pelvic Pain Syndrome
Procedure: laparoscopic prostatectomy
Phase 2

Study Type: Interventional
Study Design: Allocation: Non-Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Single Group Assignment
Masking: Open Label
Primary Purpose: Treatment
Official Title: Laparoscopic Prostatectomy for Chronic Prostatitis

Resource links provided by NLM:

Further study details as provided by The Krongrad Institute:

Primary Outcome Measures:
  • NHI CPSI (chronic prostatitis symptom index) [ Time Frame: 3 years ] [ Designated as safety issue: No ]

Estimated Enrollment: 100
Study Start Date: October 2008
Estimated Study Completion Date: October 2015
Estimated Primary Completion Date: October 2015 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: one
laparoscopic prostatectomy
Procedure: laparoscopic prostatectomy
laparoscopic prostatectomy
Other Names:
  • laparoscopic radical prostatectomy
  • minimally invasive prostate surgery


Ages Eligible for Study:   30 Years and older
Genders Eligible for Study:   Male
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • Age 30 and greater
  • NIH-CPSI score of 25 and higher
  • Symptom duration of at least one year
  • Failed treatment with antibiotics and/or other medications

Exclusion Criteria:

  • Inability to tolerate Anesthesia
  • Inability to speak any English
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT00775515

Contact: Arnon Krongrad, MD 305-936-0474
Contact: Ruth Krongrad, BSC 305-936-0474

United States, Florida
The Krongrad Institute Recruiting
Aventura, Florida, United States, 33180
Contact: Ruth Krongrad, BSC    305-936-0474   
Principal Investigator: Arnon Krongrad, MD         
Sponsors and Collaborators
The Krongrad Institute
Principal Investigator: Arnon Krongrad, MD The Krongrad Institute
  More Information

Additional Information:
Krongrad A, Lai S: Laparoscopic Prostatectomy for Severely Symptomatic, Treatment-Refractory Chronic Prostatitis: Preliminary Observations from an Ongoing Phase II Clinical Trial. UroToday Int J. 2011 Apr;4(2)

Responsible Party: ARNON KRONGRAD,M.D., THE KRONGRAD INSTITUTE Identifier: NCT00775515     History of Changes
Other Study ID Numbers: 20081635
Study First Received: October 17, 2008
Last Updated: April 29, 2011
Health Authority: United States: Institutional Review Board

Keywords provided by The Krongrad Institute:

Additional relevant MeSH terms:
Chronic Disease
Pelvic Pain
Disease Attributes
Genital Diseases, Male
Pathologic Processes
Prostatic Diseases
Signs and Symptoms processed this record on October 09, 2015