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Skin Imaging With Technologies in Development

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ClinicalTrials.gov Identifier: NCT00764920
Recruitment Status : Recruiting
First Posted : October 2, 2008
Last Update Posted : June 29, 2022
Sponsor:
Information provided by (Responsible Party):
Kristen Kelly, University of California, Irvine

Study Description
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Brief Summary:
The purpose of this research is to develop non-invasive imaging modalities for assessment of skin. This is a pilot study which will use multiple imaging modalities to collect information on normal and lesional skin. The researchers understand that the purpose of this study is not to evaluate any particular treatment and an investigation of a new therapeutic intervention would require an additional protocol. Skin conditions to be studied include vascular lesions, pigmentary disorders, inflammatory conditions and neoplasms.

Condition or disease Intervention/treatment
Pigmented Skin Lesion of Uncertain Nature Device: non-invasive imaging modalities for assessment of skin

Detailed Description:

Normal and lesional skin will be assessed by the following imaging modalities:

  1. Laser Speckle Imaging can provide information about relative blood flow in a tissue. In skin it can be used to determine what areas have more blood flow and whether a particular intervention or treatment affects blood flow.
  2. Optical Coherence Tomography and Optical Doppler Tomography can provide pictures of blood vessels in an area of the body and can also tell how fast blood is flowing in that area.
  3. Photon Migration Spectroscopy can provide information about the amount of blood, oxygen, fat and water is in a tissue.
  4. Multi-Spectral Imaging can provide a 3 dimensional image of structures within the skin.
  5. Multiphoton Microscopy can provide images of structures of the skin.
Study Design
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Study Type : Observational
Estimated Enrollment : 750 participants
Observational Model: Other
Time Perspective: Other
Official Title: Non-invasive Imaging Modalities for Assessment of Normal and Lesional Skin
Study Start Date : October 2008
Estimated Primary Completion Date : December 2024
Estimated Study Completion Date : December 2024

Resource links provided by the National Library of Medicine


Groups and Cohorts
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Group/Cohort Intervention/treatment
Skin Imaging
non-invasive imaging modalities for assessment of skin
 Device: non-invasive imaging modalities for assessment of skin
skin imaging


Outcome Measures
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Primary Outcome Measures :
  1. Collect information on normal and lesional skin [ Time Frame: up to 12 weeks ]
    Develop non-invasive imaging modalities for assessment of skin.


Eligibility Criteria
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Ages Eligible for Study:   7 Years and older   (Child, Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
Study population will be selected from University of California Irvine Medical Clinic
Criteria

Inclusion Criteria:

  • adult male or female 7 and older; able to carry out study instructions

Exclusion Criteria:

  • Younger than 7 years old
  • pregnant woman
  • breast feeding
Contacts and Locations
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Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00764920


Contacts
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Contact: Hanna Kim, MA 949-824-9265 hhkim3@uci.edu

Locations
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United States, California
Beckman Laser Institute Medical clinic Recruiting
Irvine, California, United States, 92612
Contact: Kristen Kelly, MD    949-824-7997    kmkelly@uci.edu   
Contact: Hanna Kim    949-824-9265    hhkim3@uci.edu   
Sub-Investigator: Bernard Choi, PhD         
Sub-Investigator: Mihaela Balu, PhD         
Sub-Investigator: Brian Wong, MD         
Sponsors and Collaborators
University of California, Irvine
Investigators
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Principal Investigator: Kristen M Kelly, MD Beckman Laser Institute University of California Irvine
More Information
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Responsible Party: Kristen Kelly, Professor Departments of Dermatology and Surgery, University of California, Irvine
ClinicalTrials.gov Identifier: NCT00764920    
Other Study ID Numbers: 20086307
First Posted: October 2, 2008    Key Record Dates
Last Update Posted: June 29, 2022
Last Verified: June 2022
Keywords provided by Kristen Kelly, University of California, Irvine:
human skin
Additional relevant MeSH terms:
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Pigmentation Disorders
Skin Diseases
Pathologic Processes