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Prospective Randomized Comparison of Clinical Results of Hand Assisted Laparoscopic Splenectomies and Open Splenectomies

This study has been completed.
Information provided by:
Istanbul University Identifier:
First received: September 17, 2008
Last updated: NA
Last verified: September 2008
History: No changes posted


Background: Although there are some comparative studies between laparoscopy and hand-assisted laparoscopic splenectomy (HALS) in splenomegaly cases, there is no study of the differences between HALS and open splenectomy (OS). Our aim was to compare the HALS and OS techniques in splenomegaly cases.

Methods: This prospective study included 27 patients undergoing splenectomy for splenic disorders at the Department of General Surgery, Istanbul Medical Faculty between February 2007 and October 2007. OS was performed on 14 patients, and HALS was performed in the other 13 patients.

Key words: HALS, open splenectomy, splenomegaly

Postoperative Pain

Study Type: Observational
Study Design: Time Perspective: Prospective
Official Title: Prospective Randomized Study Between Open and Hand Assisted Splenectomies

Resource links provided by NLM:

Further study details as provided by Istanbul University:

Enrollment: 27
Study Start Date: February 2007
Study Completion Date: January 2008
Primary Completion Date: October 2007 (Final data collection date for primary outcome measure)
  Show Detailed Description


Ages Eligible for Study:   Child, Adult, Senior
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population
Patients with splenomegaly who will have splenectomy procedures either open or HALS

Inclusion Criteria:

  • Splenomegaly 15 cm or longer spleens
  • Patient confirmation to join the study

Exclusion Criteria:

  • Normal sized spleens
  • Patient denial
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT00754806

Sponsors and Collaborators
Istanbul University
Principal Investigator: UMUT BARBAROS, ASSIST.PROF Istanbul Fcaulty of Medicine
  More Information

Responsible Party: Istanbul Faculty of Medicine, Department of General Surgery Identifier: NCT00754806     History of Changes
Other Study ID Numbers: 1687-2007
Study First Received: September 17, 2008
Last Updated: September 17, 2008

Keywords provided by Istanbul University:
open splenectomy
HALS as a hybrid approach of pure laparoscopy and open surgery has some definite advantages over open surgery
In the HALS group, incision length is significantly shorter
In the HALS group, postoperative pain is less than with open surgery
In the HALS group, postoperative hospital stay is shorter than with open surgery

Additional relevant MeSH terms:
Pain, Postoperative
Neurologic Manifestations
Nervous System Diseases
Postoperative Complications
Pathologic Processes
Signs and Symptoms processed this record on September 25, 2017