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Subcuticular Suture Versus Synthetic Glue in Thyroidectomy Incision (SCSvsSG)

This study has been completed.
Information provided by:
Azienda Ospedaliera - Universitaria di Modena Identifier:
First received: September 16, 2008
Last updated: May 3, 2010
Last verified: March 2009
The aim of this study is to compare aesthetic results of two different type of sutures (subcuticular versus synthetic glue) in post-thyroidectomy incisions. It is a randomized clinical trial (single blinded) designed as a superiority study, since in the authors' hypotheses glue can give better results compared with subcuticular suture in this particular district. Secondary objective is to investigate if other factors (like the use of cold/warm blade, the sex, the presence of diabetes, the lenght of incision) can influence aesthetic results.

Condition Intervention
Goiter Thyroid Neoplasms Parathyroid Pathologies Device: Octylcyanoacrylate (Dermabond) Device: Subcuticular reabsorbable suture (Caprosyn)

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single (Outcomes Assessor)
Official Title: Comparison of Esthetic Results Between Subcuticular Suture and Synthetic Glue in Thyroidectomy Incision: a RCT

Further study details as provided by Azienda Ospedaliera - Universitaria di Modena:

Primary Outcome Measures:
  • Scar evaluation scale for short term esthetic results (Hollander, J. E., Singer, A. J., Valentine, S., and Henry, M. C. Wound registry: Development and validation. Ann. Emerg. Med. 25: 675, 1995.) [ Time Frame: 10 days ]

Secondary Outcome Measures:
  • Scar Evaluation Scale (by Adam J. Singer, M.D. et al. "Development and Validation of a Novel Scar Evaluation Scale" Plastic and Reconstructive Surgery ,December 2007 Volume 120, Number 7 ,1892-1897) [ Time Frame: 3 months ]

Enrollment: 100
Study Start Date: September 2008
Study Completion Date: May 2010
Primary Completion Date: May 2010 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: A
Patients underwent thyroidectomy, emithyroidectomy, parathyroidectomy sutured with synthetic glue
Device: Octylcyanoacrylate (Dermabond)
Synthetic glue for surgical use (skin closure)
Other Name: Dermabond
Active Comparator: B
Patients underwent thyroidectomy, emithyroidectomy, parathyroidectomy sutured with subcuticular suture
Device: Subcuticular reabsorbable suture (Caprosyn)
Every stitch is positioned in the subcuticular tissue by a continuous technique
Other Name: Caprosyn


Ages Eligible for Study:   Child, Adult, Senior
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • Patients underwent thyroidectomy, emithyroidectomy, parathyroidectomy

Exclusion Criteria:

  • Former neck operations with external incisions
  • Post-operative bleeding
  • Cervical nodes involvement (with the necessity of widened incisions)
  Contacts and Locations
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Please refer to this study by its identifier: NCT00754182

Policlinico di Modena
Modena, Italy, 41100
Sponsors and Collaborators
Azienda Ospedaliera - Universitaria di Modena
Principal Investigator: Matteo Alicandri-Ciufelli, MD Otorinolaringoiatria, Policlinico di Modena
  More Information

Responsible Party: Matteo Alicandri-Ciufelli, U.O.C. Otorinolaringoiatria Azienda Ospedaliero-Univeritaria di Modena Identifier: NCT00754182     History of Changes
Other Study ID Numbers: 2454/C.E.
Study First Received: September 16, 2008
Last Updated: May 3, 2010

Keywords provided by Azienda Ospedaliera - Universitaria di Modena:
synthetic glue
subcuticular suture

Additional relevant MeSH terms:
Thyroid Neoplasms
Endocrine Gland Neoplasms
Neoplasms by Site
Head and Neck Neoplasms
Endocrine System Diseases
Thyroid Diseases processed this record on August 23, 2017