MEDEX Hidden Valley 2008
|ClinicalTrials.gov Identifier: NCT00731510|
Recruitment Status : Completed
First Posted : August 11, 2008
Last Update Posted : March 31, 2017
During a multi−week expedition to the Himalaya, we aim to investigate i) whether dietary supplementation with carbohydrate drinks and gels can improve physical performance; and ii) the underlying mechanisms for any observed changes in performance.
We hypothesise that i) carbohydrate supplementation will improve physical performance; and ii) the underlying mechanism of this improvement in performance will include maintenance of body glycogen (sugar) stores, prevention of dehydration and decrease in the incidence of acute mountain sickness.
|Condition or disease||Intervention/treatment||Phase|
|Hypoxia||Dietary Supplement: Carbohydrate energy drink Dietary Supplement: Aspartame||Not Applicable|
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||44 participants|
|Intervention Model:||Factorial Assignment|
|Masking:||Triple (Participant, Investigator, Outcomes Assessor)|
|Official Title:||MEDEX Hidden Valley 2008|
|Study Start Date :||June 2008|
|Actual Primary Completion Date :||October 2008|
|Actual Study Completion Date :||December 2008|
Carbohydrate supplements (drinks and gels)
Dietary Supplement: Carbohydrate energy drink
Complex carbohydrates including maltodextrin (97%) dissolved in water to make a a 10% solution, or dissolved in 25mL gels. Ad libitum. Twenty two days.
Other Name: PSP22 Energy, Science in Sport, Blackburn, UK
Placebo Comparator: 2
Primarily Aspartame plus natural flavourings. Powder dissolved in water to provide non-distinguishable placebo drink.
Dietary Supplement: Aspartame
Aspartame dissolved in water, ad libitum, 22 days.
Other Name: Science in Sport, Blackburn, UK
- Performance (time to complete a physical performance task) [ Time Frame: Mid study ]
- Body composition [ Time Frame: Pre, mid and post study ]
- Hydration status [ Time Frame: Pre, mid and post study ]
- Body glucose stores [ Time Frame: Pre, mid and post study ]
- Oxygen delivery [ Time Frame: Pre, mid and post study ]
- Acute mountain sickness [ Time Frame: Every day ]
- Spontaneous physical activity level [ Time Frame: Pre, mid and post study ]
- Rating of perceived exertion during a stepping task [ Time Frame: Pre, mid and post study ]
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00731510
|Medical Expeditions Ltd|
|Pinfold, Hyssington, Montgomery, Powys, United Kingdom, SY15 6AY|
|Principal Investigator:||Jamie H Macdonald, PhD||Bangor University|
|Principal Investigator:||Samuel J Oliver, PhD||Bangor University|