The Acute Effect of Atorvastain on Renal Function in Patients With Type II Diabetes
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We wanted to test the hypothesis that acute treatment with atorvastatin changes renal sodium excretion, glomerular filtration rate, tubular function and vasoactive hormones in patients with type II diabetes, not in treatment with insulin.
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Ages Eligible for Study:
40 Years to 70 Years (Adult, Older Adult)
Sexes Eligible for Study:
Accepts Healthy Volunteers:
Age: 40-70 yrs
estimated GFR between 30 and 90 ml/min
Fertile women had to use oral contraceptives or IUD
Treatment with insulin
Cerobrovascular insult or other disease of the brain
Insufficiency of the heart or lungs
Liverdisease with ALAT > 200 U/L
hemoglobin < 7,0 mmol/l
Medical treatment with psycopharmaca or/and analgetics
Pregnancy and breast feeding, 10 blood donation one month before the study.