Comparative Performance of a Bausch & Lomb Multipurpose Solution and Alcon OptiFree Replenish Multipurpose Solution
![]() |
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. |
ClinicalTrials.gov Identifier: NCT00636194 |
Recruitment Status
:
Completed
First Posted
: March 14, 2008
Results First Posted
: February 15, 2011
Last Update Posted
: December 13, 2011
|
- Study Details
- Tabular View
- Study Results
- Disclaimer
- How to Read a Study Record
Condition or disease | Intervention/treatment | Phase |
---|---|---|
Adverse Effect of Contact Lens Solution | Device: Bausch & Lomb Multipurpose Solution Device: Alcon OptiFree Replenish Multipurpose Solution | Not Applicable |
Study Type : | Interventional (Clinical Trial) |
Actual Enrollment : | 361 participants |
Allocation: | Randomized |
Intervention Model: | Parallel Assignment |
Masking: | Double (Participant, Investigator) |
Primary Purpose: | Supportive Care |
Official Title: | Product Performance of Bausch & Lomb Multi-Purpose Solution Compared to Alcon Opti-Free Replenish Multi-Purpose Solution When Used With Silicone Hydrogel Contact Lenses Worn on a Daily Wear Basis |
Study Start Date : | February 2008 |
Actual Primary Completion Date : | March 2008 |
Actual Study Completion Date : | April 2008 |

Arm | Intervention/treatment |
---|---|
Experimental: B&L Multipurpose solution
Bausch & Lomb Multipurpose Contact Lens Solution
|
Device: Bausch & Lomb Multipurpose Solution
daily care of contact lenses
|
Active Comparator: Alcon Multipurpose Solution
Alcon OptiFree Replenish Multipurpose Contact Lens Solution
|
Device: Alcon OptiFree Replenish Multipurpose Solution
daily care for contact lenses
|
- Subjective Assessment of Comfort and Cleanliness [ Time Frame: 7 days ]Scale from 0-100 for each eye where 100=most favorable rating and 0=the least favorable rating.
- Symptoms and Complaints [ Time Frame: 2 weeks ]Scores on a scale from 0 to 100, with 100 being the most favorable. Eyes with multiple unscheduled visits in a visit category were counted once for their lowest score.
- Graded Slit Lamp Findings > Grade 2 [ Time Frame: 2 week follow-up visit ]Grade none (no findings) - grade 4 (severe findings). Eyes in the Test group were compared with eyes in the Control group. Slit lamp finding greater than Grade 2.

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.
Ages Eligible for Study: | 18 Years and older (Adult, Senior) |
Sexes Eligible for Study: | All |
Accepts Healthy Volunteers: | No |
Inclusion Criteria:
- Subjects are adapted wearers of silicone hydrogel contact lenses
- VA correctable to 0.3 LogMAR or better (driving vision)
- Clear central cornea
- Subject uses a lens care system on a regular basis
Exclusion Criteria:
- Systemic disease affecting ocular health
- Using systemic or topical medications
- wear a monovision, multifocal or toric contact lenses
- Any grade 2 or greater slit lamp findings

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00636194
Malaysia | |
Laser Focus Sdn Bhd, Vision Correction Centre | |
Jalan Kuning, Tamn Pelangi, Johor Bahru, Malaysia, 80400 |
Study Director: | Mohinder Merchea, OD, PhD | Bausch & Lomb Incorporated |
Responsible Party: | Bausch & Lomb Incorporated |
ClinicalTrials.gov Identifier: | NCT00636194 History of Changes |
Other Study ID Numbers: |
562 |
First Posted: | March 14, 2008 Key Record Dates |
Results First Posted: | February 15, 2011 |
Last Update Posted: | December 13, 2011 |
Last Verified: | December 2011 |
Additional relevant MeSH terms:
Pharmaceutical Solutions Dipivefrin Contact Lens Solutions Adrenergic Agonists Adrenergic Agents |
Neurotransmitter Agents Molecular Mechanisms of Pharmacological Action Physiological Effects of Drugs Disinfectants Anti-Infective Agents |