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Randomised Controlled Trial of Intubation With the McGrath Series 5 Video Laryngoscope vs the Macintosh Laryngoscope

This study has been completed.
Information provided by:
NHS Grampian Identifier:
First received: March 4, 2008
Last updated: July 29, 2011
Last verified: March 2008

The simplicity of use and intuitive function of the McGrath video-laryngoscope suggests it may have a bigger role than as a back-up to conventional direct laryngoscopy and could possibly be the first-line laryngoscope for situations where difficult intubations are more likely or more hazardous. The incidence of difficult or failed intubation for an individual anaesthetist is related to their experience, decreasing as experience increases. The purpose of this trial is to evaluate the McGrath laryngoscope when used by relatively inexperienced anaesthetists, who are those most likely to encounter difficulties.

The null hypotheses to be tested is that there is no difference between the Macintosh and McGrath laryngoscope in terms of ease and success in intubation.

Condition Intervention
Tracheal Intubation Device: McGrath Device: Tracheal intubation using Macintosh Laryngoscope

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single (Participant)
Primary Purpose: Treatment
Official Title: Randomised Controlled Trial of Intubation With the McGrath Series 5 Video Laryngoscope vs the Macintosh Laryngoscope

Further study details as provided by NHS Grampian:

Primary Outcome Measures:
  • Intubation Time [ Time Frame: At intubation ]
    Time from anaesthetist picking up laryngoscope until 1st upward capnograph deflection after intubation

Secondary Outcome Measures:
  • Difference in Learning to Use the Scopes [ Time Frame: At analysis ]
    Is there a difference between trainee anaesthetists in learning to use the scopes

  • Quality of View of the Vocal Cords [ Time Frame: At analysis ]
  • Number of Attempts to Secure Successful Intubation [ Time Frame: At analysis ]
    Is there a difference in the number of attempts required to secure successful intubation ?

  • Incidence of Initial Oesophageal Intubation [ Time Frame: At analysis ]
  • Number of Intubations Taking More Than 70 Seconds [ Time Frame: At Analysis ]
  • Incidence of Low Arterial Saturation During Intubation [ Time Frame: At analysis ]
  • Incidence of Visible Trauma to the Airway [ Time Frame: At analysis ]

Enrollment: 120
Study Start Date: February 2008
Study Completion Date: August 2008
Primary Completion Date: August 2008 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Active Comparator: Intubation c McGrath videolaryngoscope
Tracheal Intubation using McGrath video-laryngoscope
Device: McGrath
Tracheal intubation, using Mcgrath video-laryngoscope
Other Name: Aircraft Medical McGrath Series 5 Video Laryngoscope
Active Comparator: Intubation using Macintosh Laryngoscope
Tracheal intubation using Macintosh Laryngoscope
Device: Tracheal intubation using Macintosh Laryngoscope
Tracheal intubation using Macintosh Laryngoscope


Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • Adults (18 years and over) scheduled for elective surgery whose anaesthetic plan would normally include oral intubation using a Macintosh laryngoscope blade after induction of general anaesthesia and who have given valid informed consent.

Exclusion Criteria:

  • Patients requiring special techniques for intubation such as rapid sequence induction
  • Adults who have learning difficulties
  • Are unconscious or very severely ill
  • Have a terminal illness; are in an emergency situation
  • Have a mental illness
  • Have dementia
  • Prisoners
  • Those who could be considered to have a particularly dependent relationship with the investigator and other vulnerable groups.
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT00633867

United Kingdom
Aberdeen Royal Hospitals, NHS Grampian
Aberdeen, UK, United Kingdom, AB25 2ZN
Sponsors and Collaborators
NHS Grampian
Principal Investigator: william brampton NHS Grampian
  More Information

Responsible Party: Doctor William Brampton, NHS Grampian Identifier: NCT00633867     History of Changes
Other Study ID Numbers: 08-so802-4
Study First Received: March 4, 2008
Results First Received: February 25, 2010
Last Updated: July 29, 2011

Keywords provided by NHS Grampian:
Tracheal intubation
time processed this record on September 19, 2017