Long Term Follow-up of Bone Mineral Density in Hormone Treated Turner Syndrome
Turner Syndrome (TS) is associated with osteopenia and osteoporosis. Reduced bone mineral density (BMD) and increased risk of fractures are present in many younger and middle-aged women with TS. The objective is therefore to describe longitudinal changes in BMD in TS.
The study is an observational follow-up study. Examinations at baseline, after 5 and 10 years.
Bone mineral density is measured by dual energy x-ray absorptiometry (DEXA) and bone turnover by bone markers.
Main Outcome Measures: Bone mineral density (BMD; grams/ square centimetre) were measured at lumbar spine, hip and the non-dominant forearm.
|Study Design:||Observational Model: Cohort
Time Perspective: Prospective
|Official Title:||Long Term Follow-up of Bone Mineral Density in Hormone Treated Turner Syndrome|
- Bone Mineral Density in columna lumbalis, collum femoris and distal ulnae Bone mineral density (BMD; grams/ square centimetre) were measured at lumbar spine, hip and the non-dominant forearm. [ Time Frame: Evey 5 years ] [ Designated as safety issue: No ]
Biospecimen Retention: Samples Without DNA
|Study Start Date:||November 1994|
|Estimated Study Completion Date:||June 2010|
|Primary Completion Date:||October 1996 (Final data collection date for primary outcome measure)|
Women with Turner syndrome
Healthy control women
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