PET Imaging of Cannabinoid CB1 Receptors Using [18F]FMPEP-d2
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ClinicalTrials.gov Identifier: NCT00598286
Recruitment Status :
First Posted : January 21, 2008
Last Update Posted : October 27, 2017
National Institute of Mental Health (NIMH)
Information provided by:
National Institutes of Health Clinical Center (CC)
The purpose of this protocol is to measure brain CB1 receptors in the hope to better understand how they work, so that one day we can understand how the CB1 receptors are involved in psychiatric, neurological, and behavioral disorders.
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Ages Eligible for Study:
18 Years to 65 Years (Adult, Older Adult)
Sexes Eligible for Study:
Accepts Healthy Volunteers:
All subjects must be healthy and aged 18-65 years, with history/physical exam, ECG, and laboratory tests within one year of the PET scan.
The volunteer must sign an informed consent form.
Current psychiatric illness, substance abuse including marijuana use, or severe systemic disease based on history and physical exam.
Laboratory tests with clinically significant abnormalities or positive urine toxicology screen.
Prior participation in other research protocols in the last year such that radiation exposure would exceed the annual limits.
Pregnancy and breast feeding.
Presence of ferromagnetic metal in the body or heart pacemaker.
Positive HIV test.
Employee of the investigative site or an immediate family member of an employee of the investigative site. Immediate family member is defined as a spouse, parent, child, or sibling, whether biological or legally adopted.