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Effect of Coffee on Gastro-Esophageal Disease in Patients With Symptoms of Reflux

This study has been completed.
Information provided by:
University of California, Davis Identifier:
First received: December 26, 2007
Last updated: July 12, 2010
Last verified: July 2010
Investigation evaluating the effect of coffee on gastro-esophageal reflux disease.

Condition Intervention
GERD Other: Coffee

Study Type: Interventional
Study Design: Intervention Model: Single Group Assignment
Masking: None (Open Label)
Primary Purpose: Supportive Care
Official Title: Effect of Coffee on Gastro-Esophageal Disease in Patients With Symptoms of Reflux

Resource links provided by NLM:

Further study details as provided by University of California, Davis:

Primary Outcome Measures:
  • coffee leads to reflux events [ Time Frame: 48 hours ]

Enrollment: 7
Study Start Date: May 2006
Study Completion Date: January 2010
Primary Completion Date: January 2010 (Final data collection date for primary outcome measure)
Intervention Details:
    Other: Coffee
    3 cups of coffee over a 24 hour period
Detailed Description:
Many patients with gastro-esophageal reflux disease (GERD) report that drinking coffee causes heartburn. The purpose of this study is to investigate the effects of coffee on gastro-esophageal acid reflux, and its relation to esophageal motility parameters in patients who are already scheduled to undergo 48 hour wireless pH testing as a result of having symptoms suggestive of GERD. The specific aims are to evaluate the effects of coffee on GERD during daily life and to elucidate the underlying pathogenic mechanism by which coffee induces reflux.

Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • persons undergoing wireless pH testing for diagnosis and treatment of GERD

Exclusion Criteria:

  • those under the age of 18
  • pregnant and lactating women
  • those who do not meet the inclusion criteria
  Contacts and Locations
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Please refer to this study by its identifier: NCT00584259

United States, California
University of California Davis Medical Center
Sacramento, California, United States, 95817
Sponsors and Collaborators
University of California, Davis
Principal Investigator: Peter Belafsky, MD, PhD University of California, Davis
  More Information

Responsible Party: Peter Belafsky, MD, Ph.D., University of California Davis Identifier: NCT00584259     History of Changes
Other Study ID Numbers: 200614348-2
Study First Received: December 26, 2007
Last Updated: July 12, 2010

Keywords provided by University of California, Davis:
Gastro-Esophageal Disease

Additional relevant MeSH terms:
Esophageal Diseases
Gastrointestinal Diseases
Digestive System Diseases processed this record on August 17, 2017