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Application and Evaluation of Transference Focused Psychotherapy Modified for Adolescents (TFP-A)

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT00571571
Recruitment Status : Unknown
Verified January 2011 by Weill Medical College of Cornell University.
Recruitment status was:  Recruiting
First Posted : December 12, 2007
Last Update Posted : January 4, 2011
Information provided by:
Weill Medical College of Cornell University

Brief Summary:

Normal adolescence requires a successful resolution of identity crisis, which results in the development of satisfying relationships, success in school/work pursuits, and achievement of personal goals. Adolescents, who do not resolve this crisis, are at high risk for problems in those areas of functioning. Transference Focused Psychotherapy for Adolescents (TFP-A) is a treatment that specifically addresses these issues, permitting adolescents to develop satisfying friendships, more appropriate interactions with authority, and achieve realistic life goals.

This study will evaluate the application of TFP-A, (a empirically validated treatment for adults with identity disturbance), to adolescents exhibiting the same behavioral and identity pathology. Subjects will be females; ages 14-21, with behaviors associated with identity problems, interpersonal difficulties with teachers, parents and/or peers, and live with their families. These adolescents will be randomly assigned to one of two treatment cells, TFP-A or Treatment as Usual (TAU). Subjects in TFP-A will receive weekly individual therapy for six months. The TAU group will receive standard individual therapy in the Outpatient Department. Both will receive medication as necessary. All subjects will participate in initial, weekly, and bi-monthly assessments during the six-month treatment period, and participate in a naturalistic follow-up study for an additional six months.


Adolescents with identity problems as seen in interpersonal, school, and/or family difficulties in the Transference Focused Psychotherapy for Adolescents (TFP-A) group will reduce these problem behaviors and improve management of their feelings and moods compared to adolescents with identity problems in the treatment as usual control group (TAU).

Condition or disease Intervention/treatment Phase
Identity Pathology Behavior Problems Behavioral: Psychotherapy Behavioral: Individual Psychotherapy Not Applicable

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Study Type : Interventional  (Clinical Trial)
Estimated Enrollment : 20 participants
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
Official Title: Application and Evaluation of Transference Focused Psychotherapy Modified for Adolescents
Study Start Date : October 2007
Estimated Primary Completion Date : December 2009
Estimated Study Completion Date : December 2009

Arm Intervention/treatment
Experimental: TFP-A
Specific aspects of TFP-A involve the setting up of a treatment contract/collaboration between patient and therapist to deal with the likely threats both to the treatment and to the patient's well being that may occur in the course of the treatment. After the behavioral symptoms of identity pathology are contained through structure and limit setting, the psychological structure that is believed to be the core of identity pathology are analyzed. In particular, treatment would involve the family in setting up the contract parameters, provide a psychoeducational component to the family and patient, inclusion of school personnel as appropriate to reinforce contract parameters, place an emphasis on the technique of clarification to understand specific emotional states.
Behavioral: Psychotherapy
Individual psychotherapy with parent collateral/psychoeducation as necessary.
Other Names:
  • TFP-A
  • Transference Focused Psychotherapy for Adolescents

Active Comparator: Control
The Control Group is treatment as usual in the outpatient clinic. Treatment in this arm will be carried out by therapists in the Outpatient Department. Treatment will be determined by the therapist(s) and carried out according to their particular orientation and their assessment of patient's needs. It is expected based on clinic data that the majority of patients will be seen at least one time per week.
Behavioral: Individual Psychotherapy
Individual psychotherapy and family interventions (as needed)

Primary Outcome Measures :
  1. Reduction in interpersonal difficulties with parents, teachers, and/or peers. Improved management of their feelings and moods. Reduction in other problems behaviors (i.e. substance use, self-injurious behaviors) [ Time Frame: Subjects will be assessed at entry, 2 month, 4 months, 6 months, 8 months 10 months, and 12 months ]

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Ages Eligible for Study:   14 Years to 21 Years   (Child, Adult)
Sexes Eligible for Study:   Female
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  1. Female Adolescents, ages 14-21
  2. A score of five out of nine critical items on the Borderline Personality Disorder Dimension Interview Scale.
  3. Have interpersonal difficulties in school, family, and/or peer functioning.
  4. Live at home with family.
  5. Willingness to attend evaluation sessions and weekly, individual therapy.

Exclusion Criteria:

  1. The presence of psychosis, substance dependence, non-verbal learning disability, antisocial behavior, and/or primary diagnoses of eating disorder, bipolar disorder, and obsessive-compulsive disorder.
  2. The need for hospitalization for symptom management.
  3. Significant cognitive impairment (Full Scale IQ <85).
  4. The presence of a life-threatening medical illness.

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT00571571

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Contact: Anna E Odom, Ph.D. 914-997-5946
Contact: Pamela A Foelsch, Ph.D. 212-213-9879

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United States, New York
New York-Presbyterian Hospital Recruiting
White Plains, New York, United States, 10605
Contact: Maura L Lehr, LCSW    914-997-5866   
Principal Investigator: Anna E Odom, Ph.D.         
Sponsors and Collaborators
Weill Medical College of Cornell University
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Principal Investigator: Anna E Odom, Ph.D. Weill Medical College of Cornell University

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Responsible Party: Anna E. Odom, Ph.D., Weill Cornell Medical College Identifier: NCT00571571     History of Changes
Other Study ID Numbers: 0610008834
First Posted: December 12, 2007    Key Record Dates
Last Update Posted: January 4, 2011
Last Verified: January 2011
Keywords provided by Weill Medical College of Cornell University:
Identity difussion
Adolescent psychotherapy
Transference Focused Psychotherapy for Adolescents
Identity crisis
Identity pathology
Additional relevant MeSH terms:
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Problem Behavior
Behavioral Symptoms