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The Application of Neck Ultrasound in the Assessment of Peripherally Inserted Central Catheter (PICC) Tip Position

This study has been completed.
Information provided by (Responsible Party):
University of Chicago Identifier:
First received: November 29, 2007
Last updated: March 17, 2014
Last verified: March 2014
Insertion of peripherally inserted central catheters (PICCs) at the bedside may result in tip malposition. This study was designed to evaluate whether the addition of ultrasound (US) inspection of the ipsilateral neck provides immediate recognition of PICCs in aberrant position facilitating catheter reposition prior to completion of the procedure.

Condition Intervention
Peripherally Inserted Central Catheter Insertion Technique
Other: Ultrasound inspection

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Diagnostic
Official Title: A Randomized, Controlled Trial Evaluating Post-Insertion Neck Ultrasound in Peripherally Inserted Central Catheter Procedures

Resource links provided by NLM:

Further study details as provided by University of Chicago:

Primary Outcome Measures:
  • Rate of PICCs in the ipsilateral internal jugular vein malposition as detected by post-procedure chest x-ray [ Time Frame: Same day ]

Secondary Outcome Measures:
  • Duration of PICC procedure. [ Time Frame: Same day. ]

Enrollment: 300
Study Start Date: October 2004
Study Completion Date: March 2006
Primary Completion Date: March 2006 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: 1 - Neck Ultrasound
post-PICC insertion ultrasound inspection of the ipsilateral neck
Other: Ultrasound inspection
post-PICC insertion Ultrasound inspection of the ipsilateral neck for PICC in a malposition (ipsilateral internal jugular vein)
No Intervention: 2 - Control
No post-PICC insertion ultrasound inspection of the ipsilateral neck


Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • Adult patients (> 18 years old) ordered for a peripherally inserted central catheter insertion

Exclusion Criteria:

  • patients unable to provide informed consent
  • previous peripheral inserted central catheter placement at the institution
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Please refer to this study by its identifier: NCT00565877

United States, Illinois
University of Chicago Medical Center
Chicago, Illinois, United States, 60637
Sponsors and Collaborators
University of Chicago
Principal Investigator: John P Kress, MD University of Chicago
  More Information

Responsible Party: University of Chicago Identifier: NCT00565877     History of Changes
Other Study ID Numbers: 13466A
Study First Received: November 29, 2007
Last Updated: March 17, 2014

Keywords provided by University of Chicago:
Peripherally inserted central catheter
malposition processed this record on May 25, 2017