ClinicalTrials.gov
ClinicalTrials.gov Menu

Effects of Acetaminophen on Hurt Feelings

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
ClinicalTrials.gov Identifier: NCT00561288
Recruitment Status : Completed
First Posted : November 20, 2007
Last Update Posted : June 25, 2008
Sponsor:
Information provided by:
University of Toronto

Brief Summary:
The purpose of the study is to investigate whether ingestion of acetaminophen reduces the experience of hurt feelings.

Condition or disease Intervention/treatment Phase
Emotional Pain Drug: acetaminophen Other: cornstarch Not Applicable

Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 60 participants
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double (Participant, Investigator)
Primary Purpose: Basic Science
Official Title: Effects of Acetaminophen on Hurt Feelings
Study Start Date : November 2007
Actual Primary Completion Date : May 2008
Actual Study Completion Date : May 2008

Resource links provided by the National Library of Medicine


Arm Intervention/treatment
Experimental: 1
2000 mg acetaminophen per day
Drug: acetaminophen
2 x 1000 mg doses per day

Placebo Comparator: 2
2000 mg cornstarch per day
Other: cornstarch
2 x 1000 mg cornstarch per day




Primary Outcome Measures :
  1. Self-reported daily hurt feelings [ Time Frame: 21 days ]

Secondary Outcome Measures :
  1. Reports of emotional states other than hurt feelings [ Time Frame: 21 days ]
  2. Evaluations of self-worth [ Time Frame: 21 days ]


Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.


Ages Eligible for Study:   17 Years and older   (Child, Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • University of Toronto undergraduate psychology student

Exclusion Criteria:

  • Alcohol consumption (more than 2 drinks per day)
  • Intake of enzyme-inducing drugs
  • Prolonged fasting/eating disorders/gastroenteritis
  • Intake of other over-the-counter or prescription analgesics
  • Liver Disorders
  • History of abuse treatment

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00561288


Locations
Canada, Ontario
University of Toronto
Toronto, Ontario, Canada, M5S 3G3
Sponsors and Collaborators
University of Toronto
Investigators
Principal Investigator: Geoff MacDonald, Ph.D. University of Toronto
Principal Investigator: Nathan DeWall, Ph.D. University of Kentucky

ClinicalTrials.gov Identifier: NCT00561288     History of Changes
Other Study ID Numbers: 20619
First Posted: November 20, 2007    Key Record Dates
Last Update Posted: June 25, 2008
Last Verified: June 2008

Keywords provided by University of Toronto:
Acetaminophen
Social Psychology
Affect
Interpersonal Rejection

Additional relevant MeSH terms:
Acetaminophen
Analgesics, Non-Narcotic
Analgesics
Sensory System Agents
Peripheral Nervous System Agents
Physiological Effects of Drugs
Antipyretics