Infections Related Central Venous Catheters (CVL)

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT00554021
Recruitment Status : Completed
First Posted : November 6, 2007
Last Update Posted : June 12, 2009
Information provided by:
National Defense Medical College, Japan

Brief Summary:
The purpose of this study is to clarify the relationship between SIRS (Systemic inflammatory response syndrome) and the infection associated with the use of central venous catheters at Critical Care center in National Defense Medical College, Japan.

Condition or disease

Detailed Description:
The doctor would remove the inserted catheter from the patient, if the patient shows SIRS. At the same time, the tip of used catheter and blood from the patient are checked whether the pathogenic bacteria exists or not by general bacterial protocol and blood culture test on a routine application. Unfortunately, these tests not always clarified their cause of SIRS. Therefore we conduct this investigation to establish the useful protocol for pathogenic bacteria. We check the pathogenic bacteria not only tip but through the whole catheter in Central Venous Catheter using general bacterial protocol and SEM observation. Additionally, we compared that sputum, urine, skin and blood from the patient for bacteria check.

Study Type : Observational
Estimated Enrollment : 60 participants
Observational Model: Cohort
Time Perspective: Prospective
Official Title: Infections Associated With the Use of Central Venous Catheters Related in Critical Care Center.
Study Start Date : November 2007
Actual Primary Completion Date : February 2008
Actual Study Completion Date : February 2008

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Critical Care

Department of Traumatology and Critical Care Medicine, National Defense Medical College

Primary Outcome Measures :
  1. Culture of bacteria with in central venous catheter. Morbidity and mortality of a patient with multiple resistant bacteria associated with use of the catheter. [ Time Frame: four months ]

Biospecimen Retention:   Samples With DNA
We will use the DNA from the only clinical isolated bacteria.

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Ages Eligible for Study:   14 Years to 95 Years   (Child, Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population
Critical Care staff

Inclusion Criteria:

  • A patient has been inserted with central venous line over 24 hours.

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT00554021

Department of Traumatology and Critical Care of Medicine
Tokorozawa, Saitama, Japan, 359-8513
Sponsors and Collaborators
National Defense Medical College, Japan
Study Director: Kahoko NISHIKAWA, PHD National Defense Medical College

Responsible Party: Kahoko Nishikawa, NDMC Identifier: NCT00554021     History of Changes
Other Study ID Numbers: NDMC-CV0001
First Posted: November 6, 2007    Key Record Dates
Last Update Posted: June 12, 2009
Last Verified: June 2009

Keywords provided by National Defense Medical College, Japan:
Central venous catheter
nosocomial infection

Additional relevant MeSH terms: