Does Aldosterone Cause Hypertension by a Non-Renal Mechanism?
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.|
|ClinicalTrials.gov Identifier: NCT00553722|
Recruitment Status : Unknown
Verified October 2007 by Shaare Zedek Medical Center.
Recruitment status was: Not yet recruiting
First Posted : November 6, 2007
Last Update Posted : November 6, 2007
|Condition or disease||Intervention/treatment||Phase|
|Hypertension Dialysis Hyperaldosteronism||Drug: Eplerenone Drug: Placebo||Phase 4|
|Study Type :||Interventional (Clinical Trial)|
|Estimated Enrollment :||27 participants|
|Intervention Model:||Crossover Assignment|
|Masking:||Triple (Participant, Care Provider, Investigator)|
|Official Title:||Does Aldosterone Cause Hypertension by a Non-Renal Mechanism?|
|Study Start Date :||November 2007|
|Estimated Study Completion Date :||November 2009|
Administer Eplerenone, 25 mg, orally twice daily for 4 weeks.
Administer Eplerenone, 25 mg,orally twice daily for 4 weeks.
Placebo Comparator: placebo
Administer a placebo tablet orally twice daily for 4 weeks
Administer a placebo tablet orally twice daily for 4 weeks.
- Significant drop in blood pressure with Eplerenone when compared to placebo. [ Time Frame: days ]
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00553722
|Contact: Linda Shavit, MD||02 firstname.lastname@example.org|
|Contact: Itzchak Slotki, MD||o2 email@example.com|
|Shaare Zedek Medical Center|
|Jerusalem, Israel, 91031|
|Contact: Linda Shavit, MD 02 6555086 firstname.lastname@example.org|
|Principal Investigator: Linda Shavit, MD|
|Principal Investigator:||Linda Shavit, MD||Shaare Zedek Medical Center|