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fMRI Investigation of Depression in Patients With Epilepsy

This study has been withdrawn prior to enrollment.
(Enrollment by invitation only)
Sponsor:
ClinicalTrials.gov Identifier:
NCT00532376
First Posted: September 20, 2007
Last Update Posted: February 10, 2009
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by:
Weill Medical College of Cornell University
  Purpose
Depression is very common in epilepsy. Depression is the strongest predictor of poor quality of life in patients with epilepsy. The biological basis for depression in epilepsy remains poorly understood. This study uses functional MRI (fMRI) to examine brain response to emotional and non-emotional stimuli in healthy control subjects and in patients with epilepsy who are either depressed or not depressed. Results from this study will contribute to a better understanding of depression in epilepsy, which may eventually inform development of better treatment modalities..

Condition
Epilepsy Depression

Study Type: Observational
Study Design: Time Perspective: Prospective
Official Title: fMRI Investigation of Depression in Patients With Epilepsy

Resource links provided by NLM:


Further study details as provided by Weill Medical College of Cornell University:

Estimated Enrollment: 250
Study Start Date: September 2005
  Eligibility

Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.


Ages Eligible for Study:   18 Years to 75 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00532376


Locations
United States, New York
Citigroup Biomedical Imaging Center at 516 East 72nd Street
New York, New York, United States, 10021
Sponsors and Collaborators
Weill Medical College of Cornell University
Investigators
Principal Investigator: Tracy A Butler, MD Weill Medical College of Cornell University
  More Information

ClinicalTrials.gov Identifier: NCT00532376     History of Changes
Other Study ID Numbers: 0601008320
First Submitted: September 19, 2007
First Posted: September 20, 2007
Last Update Posted: February 10, 2009
Last Verified: February 2009

Keywords provided by Weill Medical College of Cornell University:
epilepsy
depression
fMRI
emotion

Additional relevant MeSH terms:
Depression
Depressive Disorder
Epilepsy
Behavioral Symptoms
Mood Disorders
Mental Disorders
Brain Diseases
Central Nervous System Diseases
Nervous System Diseases