The Use of Irvingia Gabonensis (Bush Mango)and Cissus Quadrangularis to Reduce Weight and Blood Lipids
|ClinicalTrials.gov Identifier: NCT00526682|
Recruitment Status : Completed
First Posted : September 10, 2007
Last Update Posted : September 10, 2007
|Condition or disease||Intervention/treatment||Phase|
|Obesity Overweight Dyslipidemia||Dietary Supplement: Irvingia/cissus combo||Not Applicable|
To assess and compare the effects of administration of Cissus quadrangularis (Linn) and a Cissus quadrangularis /Irvingia gabonensis combination on body weight blood pressure, fasting blood glucose, plasma total and LDL cholesterol in 72 overweight and obese subjects.
The study was a 10 week randomized, double-blind, placebo-controlled design, involving 72 obese or overweight participants. Participants were randomly divided into three groups (24 participants/ group):
Group 1 - Placebo; Group 2 - Cissus quadrangularis (CQ); Group 3 - Cissus quadrangularis and Irvingia gabonensis (CQ-IG).
The placebo (250mg) or active formulations ((150 mg CQ and 250 mg CQ-IG) were administered twice daily before meals. Weight as well as fasting blood was taken at baseline, and at 4, 8 and 10 weeks.
No major dietary changes or exercises were suggested during the study.
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||72 participants|
|Intervention Model:||Parallel Assignment|
|Masking:||Triple (Participant, Care Provider, Investigator)|
|Official Title:||The Effect of Combining Cissus Quadrangularis and Irvingia Gabonensis on Obesity and Obesity Related Diseases|
|Study Start Date :||January 2007|
|Actual Study Completion Date :||April 2007|
Active Comparator: 1
Comparison of actives for synergy
Dietary Supplement: Irvingia/cissus combo
Other Name: Irvingia cissus combo
- Weight change [ Time Frame: 10 weeks ]
- Blood lipids Body fat Fasting blood glucose [ Time Frame: 10 weeks ]
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00526682
|Principal Investigator:||Julius E OBEN, PhD||University of Yaounde 1|