Metabolic Changes in Hypothyroid Patients
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.|
|ClinicalTrials.gov Identifier: NCT00524238|
Recruitment Status : Completed
First Posted : September 3, 2007
Last Update Posted : February 12, 2008
Hypothyroidism is a frequent condition in danish women, but often overlooked. Along with fatigue one of the main symptoms is weight gain as a result to significantly decreased energy expenditure.
This study was undertaken to elucidate changes in glucose, lipid and amino acid turnover in these patients.
|Condition or disease||Intervention/treatment||Phase|
|Hypothyroidism||Drug: L-thyroxine||Not Applicable|
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||22 participants|
|Intervention Model:||Single Group Assignment|
|Masking:||None (Open Label)|
|Primary Purpose:||Basic Science|
|Official Title:||Impact of Hypothyroidism on Glucose, Lipid, and Amino Acid Turnover|
|Study Start Date :||March 2004|
|Actual Primary Completion Date :||August 2006|
|Actual Study Completion Date :||August 2006|
11 hypothyroid patients, newly diagnosed, examined before and after treatment
The hypothyroid patients receive usual treatment with L-thyroxine in our out patient clinic. The doctors there subscribe the medication, this study has no protocol regarding this, we observe the patients again after having been biochemically euthyroid for at least two months.
No Intervention: 2
10 healthy controls
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00524238
|Aarhus University Hospital|
|Aarhus, Denmark, 8000|
|Principal Investigator:||Signe Gjedde, MD||Aarhus University, Clinical Institute|