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A Randomized Controlled Trial on the Effect of Exercise on Physical, Cognitive and Affective Function in Dementia Subjects

The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified July 2010 by Hospital Authority, Hong Kong.
Recruitment status was:  Recruiting
Information provided by:
Hospital Authority, Hong Kong Identifier:
First received: July 6, 2007
Last updated: July 6, 2010
Last verified: July 2010

Studies have shown conflicting results of the effect of exercise on dementia patients.

The aim of this study is to examine the role of physical activity on the risk of cognitive impairment and dementia in older persons.

To promote the benefits of aerobic exercise on dementia patients and encourage exercise prescription in the management of dementia subjects.

Condition Intervention
Dementia Procedure: Aerobic exercise training

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single
Official Title: To Study the Effect of Exercise Training in Term of Aerobic Exercise for 3 Months, on the Physical, Cognitive and Affective Function in Dementia Subjects

Resource links provided by NLM:

Further study details as provided by Hospital Authority, Hong Kong:

Primary Outcome Measures:
  • Physical function measurement using SF-12 [ Time Frame: every 3 months for 1 year ]
  • Affective function measurement by Cornell depression score [ Time Frame: every 3 months for 1 year ]
  • Cognitive function by MMSE and ADAS-cog [ Time Frame: every 3 months for 1 year ]

Secondary Outcome Measures:
  • 6 minutes walk, functional reach, Berg balance scale [ Time Frame: every 3 months for 1 year ]
  • Carer stress scale [ Time Frame: every 3 months for 1 year ]
  • No. of fall/restricted activity days/time spend in exercise or walking [ Time Frame: every 3 months for 1 year ]

Estimated Enrollment: 64
Study Start Date: January 2006
Estimated Study Completion Date: October 2007

Ages Eligible for Study:   60 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All

Inclusion Criteria:

  • MMSE<26
  • Age >60
  • Community dwelling and ambulatory
  • Have a caregiver that is willing to participate and escort patient to hospital for training and assessment

Exclusion Criteria:

  • MMSE<10
  • live in old age home
  • poor mobility, unable to attend exercise training
  • no carer to bring patient to attend hospital training
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT00497822

Contact: Doris KY Miu, Dr (852) 3517 5326

Kwong Wah Hospital Recruiting
Hong Kong, China
Sub-Investigator: Ying Fai Mak, Dr         
Sponsors and Collaborators
Hospital Authority, Hong Kong
Principal Investigator: Doris KY Miu, Dr Department of Medicine and Geriatrics, Kwong Wah Hospital
  More Information

Additional Information: Identifier: NCT00497822     History of Changes
Other Study ID Numbers: KW/EX05-090
Study First Received: July 6, 2007
Last Updated: July 6, 2010

Keywords provided by Hospital Authority, Hong Kong:

Additional relevant MeSH terms:
Brain Diseases
Central Nervous System Diseases
Nervous System Diseases
Neurocognitive Disorders
Mental Disorders processed this record on August 23, 2017