Pre-operative Rehabilitation Exercise Program for Total Knee Arthroplasty (PREP)
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|ClinicalTrials.gov Identifier: NCT00493142|
Recruitment Status : Active, not recruiting
First Posted : June 28, 2007
Last Update Posted : September 16, 2016
|Condition or disease||Intervention/treatment||Phase|
|Osteoarthritis Rheumatoid Arthritis||Behavioral: Exercise||Not Applicable|
Patients with lower levels of function prior to total knee arthroplasty (TKA) attain lower functional endpoints after surgery. Therapeutic exercise improves function in patients with arthritis of the knee, yet little evidence has examined the impact of pre-operative exercise for TKA.
Single blinded randomized clinical trial comparing a pre-operative home exercise program to pre-operative usual care for patients who are waiting for TKA.Comparison group is usual care within the health region which does not include pre-operative rehabilitation program.
Primary outcome: WOMAC function subscale. Secondary outcomes: 1) quality of life; 2) ambulation; 3) self-efficacy; 4) anxiety; 5) patient satisfaction; 6) cost-effectiveness of this intervention.
Total Enrollment: 230 patients
If the intervention improves function prior to surgery, results will be clinically applicable for patients waiting for surgery
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||240 participants|
|Intervention Model:||Single Group Assignment|
|Masking:||Double (Investigator, Outcomes Assessor)|
|Official Title:||Impact of a Pre-operative Rehabilitation Exercise Program for Patients With Severe Dysfunction Awaiting Total Knee Arthroplasty|
|Study Start Date :||July 2008|
|Actual Primary Completion Date :||July 2013|
|Estimated Study Completion Date :||June 2017|
physical therapy home exercise
- Self-reported function [ Time Frame: 5 evaluations within 6 months after surgery ]
- Quality of life, self-efficacy, ambulation, anxiety and patient satisfaction [ Time Frame: 5 evaluations within 6 months after surgery ]
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00493142
|University of Alberta- Capital Health|
|Edmonton, Alberta, Canada, T6G 2G4|
|Principal Investigator:||Allyson Jones, PhD||University of Alberta|
|Study Director:||Lauren Beaupre, PhD||Capital Health- UAH|