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Study of Myopia Acquisition and Prevention (SMART)

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ClinicalTrials.gov Identifier: NCT00477620
Recruitment Status : Completed
First Posted : May 24, 2007
Last Update Posted : February 23, 2009
Information provided by:

Study Description
Brief Summary:


To determine whether the use of reading glasses blocks the near work mediated increased incidence of myopia in healthy school children.


SMART enrolled 115 emmetropic children (ages 7-9 years). The children were recruited in the Principality of Liechtenstein. They were randomly assigned to either the control group (n=52) or to receive reading glasses with a lens power of +2.0 dioptres (n=63). The primary outcome measure was progression towards myopia as determined by autorefraction after cycloplegia. The secondary outcome measure was change in biometry measurements of corneal curvature, axial length, anterior chamber depth, crystalline lens thickness, and vitreous chamber depth using partial coherence interferometry.

Condition or disease Intervention/treatment
Myopia Behavioral: Wearing of reading glasses during prolonged near work

Study Design

Study Type : Interventional  (Clinical Trial)
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)
Primary Purpose: Prevention
Official Title: Study of Myopia Acquisition and Prevention in a Randomised Trial
Study Start Date : April 2004
Primary Completion Date : October 2008
Study Completion Date : October 2008
Arms and Interventions

Outcome Measures

Eligibility Criteria

Information from the National Library of Medicine

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Ages Eligible for Study:   7 Years to 9 Years   (Child)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes

Inclusion Criteria:

  • Emmetropia

Exclusion Criteria:

  • Ametropia
Contacts and Locations

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00477620

Sponsors and Collaborators
University Hospital Freiburg
Study Chair: Alexaner Reis, PD Dr. med. Augenwerk Liechtenstein
More Information

ClinicalTrials.gov Identifier: NCT00477620     History of Changes
Other Study ID Numbers: FR-2005-01-01
First Posted: May 24, 2007    Key Record Dates
Last Update Posted: February 23, 2009
Last Verified: February 2009

Keywords provided by University Hospital Freiburg:

Additional relevant MeSH terms:
Refractive Errors
Eye Diseases