Study of Genetic Polymorphisms in Thai HIV-1 Infected Patients on SQV/r
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ClinicalTrials.gov Identifier: NCT00476502 |
Recruitment Status
:
Completed
First Posted
: May 22, 2007
Last Update Posted
: April 5, 2012
|
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Condition or disease | Intervention/treatment |
---|---|
HIV Infections | Genetic: identify genetic polymorphism in Thai HIV infected |
Study Type : | Observational |
Actual Enrollment : | 250 participants |
Observational Model: | Cohort |
Time Perspective: | Cross-Sectional |
Official Title: | Study of Genetic Polymorphisms of CYP 3A and MDR-1 Genes in Thai HIV-1 Infected Patients on Saquinavir/Ritonavir |
Study Start Date : | February 2006 |
Actual Primary Completion Date : | December 2008 |
Actual Study Completion Date : | December 2008 |
Group/Cohort | Intervention/treatment |
---|---|
1
patients involved in structured interruption therapy
|
Genetic: identify genetic polymorphism in Thai HIV infected
Gene sequencing of Cyp450 metabolic pathway
|

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Ages Eligible for Study: | 18 Years and older (Adult, Senior) |
Sexes Eligible for Study: | All |
Accepts Healthy Volunteers: | No |
Sampling Method: | Probability Sample |
Inclusion Criteria:
- HIV-infected persons who have been enrolled in the Staccato study
- On low-dose ritonavir boosted saquinavir at the time blood samples are collected
Exclusion Criteria:
- Inability to understand the nature and extent of the study and the procedures required

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00476502
Thailand | |
The HIV Netherlands Australia Thailand Research Collaboration (HIV-NAT) | |
Bangkok, Thailand, 10330 |
Principal Investigator: | Kiat Ruxrungtham, MD | The HIV Netherlands Australia Thailand Research Collaboration (HIV-NAT) |
Additional Information:
Responsible Party: | The HIV Netherlands Australia Thailand Research Collaboration |
ClinicalTrials.gov Identifier: | NCT00476502 History of Changes |
Other Study ID Numbers: |
HIV-NAT 031 |
First Posted: | May 22, 2007 Key Record Dates |
Last Update Posted: | April 5, 2012 |
Last Verified: | April 2012 |
Keywords provided by The HIV Netherlands Australia Thailand Research Collaboration:
genetic polymorphism CYP 3A MDR-1 |
Thai HIV Treatment Experienced |
Additional relevant MeSH terms:
HIV Infections Lentivirus Infections Retroviridae Infections RNA Virus Infections Virus Diseases |
Sexually Transmitted Diseases, Viral Sexually Transmitted Diseases Immunologic Deficiency Syndromes Immune System Diseases |