Correlation Between Serum Markers of Unstable Plaque and Virtual Histology of Unstable Plaque Visualized by IVUS

This study has been completed.
Information provided by:
Ziv Hospital Identifier:
First received: April 25, 2007
Last updated: August 23, 2009
Last verified: April 2007

Thirty patients scheduled to coronary angiography and IVUS in according to their treating physician decision will be enrolled in the study. The coronary angiography and IVUS will be done on according to regular clinical standards.

As the study protocol, 40 cc of blood will be drawn from the patients after written informed consent.

The laboratory tests will be processed for the above mentioned serum markers of unstable plaque.

A multivariate correlation test will be done between the different serum markers and the plaque morphology by angiography and composition (virtual histology) by IVUS.

Acute Coronary Thrombose
Plaque Rupture
Acute Coronary Syndrome

Study Type: Observational
Study Design: Observational Model: Case-Only
Time Perspective: Prospective
Official Title: Correlation Between Serum Markers of Unstable Plaque and Virtual Histology of Unstable Plaque Visualized by IVUS

Further study details as provided by Ziv Hospital:

Estimated Enrollment: 30
Study Start Date: April 2007
Study Completion Date: May 2009
Primary Completion Date: April 2008 (Final data collection date for primary outcome measure)
  Show Detailed Description


Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population

Patients scheduled to coronary angiography and IVUS


Inclusion Criteria:

  • Both genders: males and females
  • Age - above 18 years
  • Patients scheduled to coronary angiography and IVUS
  • Written Informed Consent Form

Exclusion Criteria:

  • Pregnant or breast-feeding woman
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT00466050

Heart Institute ,Ziv Medical Center
Safed, Israel, 13110
Sponsors and Collaborators
Ziv Hospital
Principal Investigator: Osamah Hussein, MD Ziv Medical Center
Principal Investigator: Alon Marmor, Prof Ziv Medical Center
  More Information


Responsible Party: Ziv Hospital Identifier: NCT00466050     History of Changes
Other Study ID Numbers: HP-7-234-S
Study First Received: April 25, 2007
Last Updated: August 23, 2009
Health Authority: Israel: Ministry of Health

Keywords provided by Ziv Hospital:
plaque rupture,
acute coronary thrombose,
coronary angiography,

Additional relevant MeSH terms:
Acute Coronary Syndrome
Angina Pectoris
Cardiovascular Diseases
Chest Pain
Heart Diseases
Myocardial Ischemia
Signs and Symptoms
Vascular Diseases processed this record on October 06, 2015