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Pulmonary Function Changes in 10 Pack Year Smokers With Chronic Bronchitis

This study has been completed.
Information provided by:
Westside Family Medical Center, P.C. Identifier:
First received: March 30, 2007
Last updated: August 13, 2008
Last verified: June 2008
To determine whether an average population of males and females who smoke 10 pack years or more of cigarettes in a primary care setting with chronic bronchitis has already developed significant changes on pulmonary function testing.

Chronic Bronchitis

Study Type: Observational
Study Design: Observational Model: Ecologic or Community
Time Perspective: Prospective
Official Title: Pulmonary Function Changes in 10 Pack Year Smokers With Chronic Bronchitis

Resource links provided by NLM:

Further study details as provided by Westside Family Medical Center, P.C.:

Estimated Enrollment: 100
Study Start Date: March 2007
Study Completion Date: August 2008
Detailed Description:
The incident of COPD is dramatically increasing while other chronic disease states are decreasing in the US population. Smoking cigarettes is the leading risk factor for COPD. Smokers with chronic bronchitis may show early or late changes of COPD on pulmonary function tests. It is imperative that we define this patient population to determine whether early intervention will alter pulmonary function over the years.

Ages Eligible for Study:   40 Years to 80 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population
Primary care

Inclusion Criteria:

  1. Subjects must sign a written informed consent.
  2. Enrollment population would include males and females 40 years of age to 80 years of age.
  3. Current history or past history of smoking at least 10 pack years of cigarettes.
  4. Patients to satisfy the diagnosis of chronic bronchitis.
  5. Non-smokers will be allowed in the control group

Exclusion Criteria:

  1. Chronic infections such as TB or other infections of the lungs.
  2. Collagen diseases such as rheumatoid arthritis or lupus which affect the lungs.
  3. Any previous lung diseases such as pneumoconiosis.
  4. Previous accidents or surgery which would involve the lungs or the ribcage.
  5. Maintenance medications used for asthma or COPD such as long acting bronchodilators or inhaled corticosteroids.
  6. Asthma patients or other patients with allergies that may affect pulmonary function test will be excluded.
  7. Any medical condition in the opinion of the investigator that would make the subject unsuitable for enrollment.
  8. Pregnant woman will not be allowed
  9. Current participation in a research study or within the last 30 days.
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Please refer to this study by its identifier: NCT00454675

United States, Michigan
Westside Family Medical Center, P.C.
Kalamazoo, Michigan, United States, 49009
Sponsors and Collaborators
Westside Family Medical Center, P.C.
Principal Investigator: Gary E Ruoff, MD Westside Family Medical Center, P.C.
  More Information

Responsible Party: Gary E. Ruoff, M.D., Westside Family Medical Center, P.C. Identifier: NCT00454675     History of Changes
Other Study ID Numbers: COPD-2006-01
Study First Received: March 30, 2007
Last Updated: August 13, 2008

Keywords provided by Westside Family Medical Center, P.C.:
Chronic Bronchitis
Pulmonary Function Test Abnormalities

Additional relevant MeSH terms:
Acute Disease
Bronchitis, Chronic
Bronchial Diseases
Respiratory Tract Diseases
Lung Diseases, Obstructive
Lung Diseases
Respiratory Tract Infections
Disease Attributes
Pathologic Processes
Pulmonary Disease, Chronic Obstructive processed this record on May 25, 2017