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Inhaled Mannitol and Ciliary Beat Frequency in COPD Patients

The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified March 2007 by Imperial College London.
Recruitment status was:  Recruiting
Information provided by:
Imperial College London Identifier:
First received: March 9, 2007
Last updated: NA
Last verified: March 2007
History: No changes posted
The main purpose of the study is to evaluate the effect of mannitol on the cilia's beat frequency (ciliary beat frequency) in COPD patients.

Chronic Obstructive Pulmonary Disease

Study Type: Observational
Study Design: Observational Model: Defined Population
Primary Purpose: Screening
Time Perspective: Cross-Sectional
Time Perspective: Prospective
Official Title: The Effect of Inhaled Mannitol on Ciliary Beat Frequency in COPD Patients

Resource links provided by NLM:

Further study details as provided by Imperial College London:


Ages Eligible for Study:   38 Years to 80 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • COPD
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT00446121

Contact: Sergei Kharitonov, MD PhD +44 02073518051
Contact: Lars Pedersen, MD +44 02073518051

United Kingdom
Airway Disease Section, Asthma Lab, Imperial College London, Royal Brompton Hospital Recruiting
London, United Kingdom, SW3 6LY
Contact: Sergei Kharitonov, MD PhD    +44 02073518051   
Contact: Lars Pedersen, MD    +44 02073518051   
Principal Investigator: Sergei Kharitonov, MD PhD         
Sub-Investigator: Lars Pedersen, MD         
Sub-Investigator: Peter J Barnes, MA DM DSc FRCP         
Sponsors and Collaborators
Imperial College London
Principal Investigator: Sergei Kharitonov, MD PhD Imperial College London
  More Information Identifier: NCT00446121     History of Changes
Other Study ID Numbers: 06/Q0410/55
Study First Received: March 9, 2007
Last Updated: March 9, 2007

Keywords provided by Imperial College London:

Additional relevant MeSH terms:
Lung Diseases
Lung Diseases, Obstructive
Pulmonary Disease, Chronic Obstructive
Respiratory Tract Diseases
Diuretics, Osmotic
Natriuretic Agents
Physiological Effects of Drugs processed this record on May 25, 2017