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Effects of Naproxen on Physical Performance

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ClinicalTrials.gov Identifier: NCT00410995
Recruitment Status : Terminated (Study never initiated.)
First Posted : December 13, 2006
Last Update Posted : October 11, 2007
Sponsor:
Information provided by:
University of Oklahoma

Brief Summary:
The purpose of this study is to determine the effect of daily use of Naproxen (a commonly used over-the-counter NSAID) on the physical performance of athletes, as measured by maximum oxygen consumption.

Condition or disease Intervention/treatment Phase
Healthy Drug: Naproxen Phase 4

Study Type : Interventional  (Clinical Trial)
Enrollment : 40 participants
Allocation: Non-Randomized
Intervention Model: Single Group Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
Official Title: Effects of Naproxen on Physical Performance
Study Start Date : May 2004
Actual Study Completion Date : August 2006

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MedlinePlus related topics: Health Checkup
U.S. FDA Resources




Primary Outcome Measures :
  1. Effects on physical performance in terms of maximum oxygen consumption


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Ages Eligible for Study:   18 Years to 30 Years   (Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  1. Age equal to or greater than18 years of age
  2. No history of allergy or adverse reaction to any NSAID
  3. No use of any NSAID in past 2 weeks
  4. No history of peptic ulcer disease (PUD), gastroesophageal disease (GERD), or gastritis
  5. No major medical history including but not limited to diabetes, hypertension, asthma, kidney disease and coronary artery disease
  6. Currently not taking any medication including oral contraceptives

Exclusion Criteria:

  1. Age < 18 years of age
  2. History of allergy or adverse reaction to any NSAID
  3. Use of any NSAID in past 2 weeks
  4. History of a bleeding disorder
  5. History of PUD, GERD, or gastritis
  6. Pregnant
  7. A medical history of diabetes, hypertension, asthma, kidney disease or coronary artery disease
  8. Taking any medication including oral contraceptives

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00410995


Locations
United States, Oklahoma
Family Practice - CMT
Tulsa, Oklahoma, United States, 74104
Sponsors and Collaborators
University of Oklahoma
Investigators
Principal Investigator: LaMont Cavanagh, MD University of Oklahoma-Tulsa

ClinicalTrials.gov Identifier: NCT00410995     History of Changes
Other Study ID Numbers: 11186
First Posted: December 13, 2006    Key Record Dates
Last Update Posted: October 11, 2007
Last Verified: October 2007

Keywords provided by University of Oklahoma:
Physically fit volunteers

Additional relevant MeSH terms:
Naproxen
Anti-Inflammatory Agents, Non-Steroidal
Analgesics, Non-Narcotic
Analgesics
Sensory System Agents
Peripheral Nervous System Agents
Physiological Effects of Drugs
Anti-Inflammatory Agents
Antirheumatic Agents
Gout Suppressants
Cyclooxygenase Inhibitors
Enzyme Inhibitors
Molecular Mechanisms of Pharmacological Action