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Investigation of Genetic Risk of Metabolic Syndrome in Company Employee (NGK Study)

The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified September 2007 by Nagoya University.
Recruitment status was:  Recruiting
Information provided by:
Nagoya University Identifier:
First received: December 6, 2006
Last updated: September 19, 2007
Last verified: September 2007
The metabolic syndrome is a highly prevalent disorder, which causes atherosclerotic cardiovascular disease and is closely associated with insulin resistance. The alteration of the secretion of adipocytokines from accumulated visceral adipose tissue in the obese induces insulin resistance. The purpose of this study is to identify gene polymorphisms that confer susceptibility to the metabolic syndrome and to make up a new health guidance program based on genetic risk assessment. About 25% of male employees over 45 years old in a certain company are diagnosed with the metabolic syndrome in medical examination. We, the researchers at Nagoya University, will analyze gene polymorphism and various biomarkers of over 3500 company employees.

Metabolic Syndrome X
Diabetes Mellitus

Study Type: Observational
Study Design: Observational Model: Case Control
Observational Model: Natural History
Time Perspective: Longitudinal
Time Perspective: Retrospective/Prospective
Official Title: Assessment of Genetic Risk of Metabolic Syndrome in Company Employee and Making New Health Guidance Program (NGK Study)

Resource links provided by NLM:

Further study details as provided by Nagoya University:

Estimated Enrollment: 4000
Study Start Date: September 2006

Ages Eligible for Study:   20 Years to 65 Years   (Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes

Inclusion Criteria:

  • Healthy subjects who work for a certain company
  Contacts and Locations
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Please refer to this study by its identifier: NCT00408824

Contact: Kenji Yasui, MD, PhD +81-52-788-6211

Department of Bio-information Analysis, Research Institute of Environmental Medicine, Nagoya University Recruiting
Nagoya, Aichi, Japan, 464-8601
Contact: Kenji Yasui, MD, PhD    +81-52-788-6211   
Principal Investigator: Kenji Yasui, MD, PhD         
Sponsors and Collaborators
Nagoya University
Study Chair: Kenji Yasui, MD, PhD Department of Bio-information Analysis, Research Institute of Environmental Medicine, Nagoya University
  More Information

Publications automatically indexed to this study by Identifier (NCT Number): Identifier: NCT00408824     History of Changes
Other Study ID Numbers: RIEM-G-3
Study First Received: December 6, 2006
Last Updated: September 19, 2007

Keywords provided by Nagoya University:
insulin resistance
Metabolic syndrome

Additional relevant MeSH terms:
Diabetes Mellitus
Metabolic Syndrome X
Pathologic Processes
Glucose Metabolism Disorders
Metabolic Diseases
Endocrine System Diseases
Insulin Resistance
Lipid Metabolism Disorders processed this record on May 25, 2017