Calcium Absorption and Retention From Marine Products

This study has been completed.
Sponsor:
Collaborator:
National Institute of Nutrition and Seafood Research, Norway
Information provided by (Responsible Party):
Arne Astrup, University of Copenhagen
ClinicalTrials.gov Identifier:
NCT00393289
First received: October 26, 2006
Last updated: July 19, 2016
Last verified: July 2016
  Purpose
The purpose of the study is to determine the uptake of calcium from fish bone meal from salmon and cod in 12 healthy volunteers. A test meal labelled with trace amounts of a radioactive calcium isotope (Ca47) will be given after an overnight fast and whole body retention of calcium will be measured on day 13, 21, and 24 after the test meal day.

Condition Intervention
Calcium Metabolism
Behavioral: Calcium controlled diet

Study Type: Interventional
Study Design: Allocation: Randomized
Endpoint Classification: Bio-availability Study
Intervention Model: Crossover Assignment
Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor)
Primary Purpose: Basic Science
Official Title: Calcium Absorption and Retention From Marine Products

Resource links provided by NLM:


Further study details as provided by University of Copenhagen:

Primary Outcome Measures:
  • Whole body retention of calcium

Secondary Outcome Measures:
  • D-vitamin and PTH status, serum calcium and phosporus, and calcium intake

Enrollment: 12
Study Start Date: November 2005
Study Completion Date: March 2007
Primary Completion Date: April 2006 (Final data collection date for primary outcome measure)
  Show Detailed Description

  Eligibility

Ages Eligible for Study:   18 Years to 40 Years   (Adult)
Genders Eligible for Study:   Male
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • healthy males
  • BMI: 18-18 kg/m2
  • age: 18-40 years

Exclusion Criteria:

  • elite athletes
  • on medication
  • gastrointestinal disorders, chronic diseaes
  • smoking
  • prior participation in radioisotpe studies
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00393289

Locations
Denmark
Institute of Human Nutirtion, The Royal Veterinary and Agricultural University, Denmark
Frederiksberg, Frederiksberg C, Denmark, 1958
Sponsors and Collaborators
University of Copenhagen
National Institute of Nutrition and Seafood Research, Norway
Investigators
Principal Investigator: Susanne Bügel, MSc, PhD Institute of Human Nutrition, THe Royal Veterinary and Agricultural University, Denmark
  More Information

Responsible Party: Arne Astrup, Professor, University of Copenhagen
ClinicalTrials.gov Identifier: NCT00393289     History of Changes
Other Study ID Numbers: KF-01270319  M182 
Study First Received: October 26, 2006
Last Updated: July 19, 2016
Health Authority: Denmark: The Danish National Committee on Biomedical Research Ethics
Individual Participant Data  
Plan to Share IPD: Yes

Keywords provided by University of Copenhagen:
Calcium absorption
D-vitamin status
Whole body calcium retention
Calcium intake
PTH status

Additional relevant MeSH terms:
Calcium, Dietary
Bone Density Conservation Agents
Physiological Effects of Drugs

ClinicalTrials.gov processed this record on August 25, 2016