Scientific Evaluation of Peer Education and STD Treatment to Reduce the Spread of HIV in Zimbabwe

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT00390949
Recruitment Status : Completed
First Posted : October 23, 2006
Last Update Posted : May 28, 2015
Biomedical Research and Training Institute
Information provided by:
Imperial College London

Brief Summary:
The purpose of this study is to determine whether community-based peer education and condom distribution combined with improved treatment of sexually transmitted infections are effective in reducing the spread of HIV infection in a sub-Saharan African population

Condition or disease Intervention/treatment Phase
HIV Infections Behavioral: Peer education among commercial sex workers and clients Behavioral: Condom distribution and promotion Procedure: Syndromic treatment of sexually transmitted infections Procedure: Systemic counselling for STI patients Not Applicable

  Show Detailed Description

Study Type : Interventional  (Clinical Trial)
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)
Primary Purpose: Prevention
Official Title: Impact and Process Evaluation of Integrated Community and Clinic-based HIV-1 Control: a Cluster-randomised Trial in Eastern Zimbabwe
Study Start Date : July 1998
Study Completion Date : February 2003

Resource links provided by the National Library of Medicine

MedlinePlus related topics: HIV/AIDS
U.S. FDA Resources

Primary Outcome Measures :
  1. HIV incidence at the community level

Secondary Outcome Measures :
  1. Self-reported genital ulcers
  2. Self-reported urethral or genital discharge
  3. Sexually transmitted infection treatment effectiveness (self-reported cessation of symptoms)
  4. Sexual behaviour change (sexual debut, sexual partner change, non-regular partners, unprotected sex with regular and casual partners)
  5. Health-seeking behaviour change
  6. HIV/AIDS knowledge

Information from the National Library of Medicine

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Ages Eligible for Study:   Child, Adult, Senior
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes

Inclusion Criteria:

  • All members of study communities

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT00390949

Biomedical Research and Training Institute
Harare, Zimbabwe
Sponsors and Collaborators
Imperial College London
Biomedical Research and Training Institute
Principal Investigator: Simon Gregson, DPhil Imperial College London
Principal Investigator: Stephen Chandiwana, PhD Biomedical Research and Training Institute

Additional Information:
Publications: Identifier: NCT00390949     History of Changes
Other Study ID Numbers: PC3239_DFID
First Posted: October 23, 2006    Key Record Dates
Last Update Posted: May 28, 2015
Last Verified: October 2006

Keywords provided by Imperial College London:
HIV prevention
Core groups
Peer education
Syndromic management
Commercial sex workers
Condom distribution
HIV Seronegativity

Additional relevant MeSH terms:
HIV Infections
Lentivirus Infections
Retroviridae Infections
RNA Virus Infections
Virus Diseases
Sexually Transmitted Diseases, Viral
Sexually Transmitted Diseases
Immunologic Deficiency Syndromes
Immune System Diseases