Changes in HIV Viral Load in Patients Undergoing Treatment for Filariasis
|ClinicalTrials.gov Identifier: NCT00344279|
Recruitment Status : Completed
First Posted : June 26, 2006
Last Update Posted : July 2, 2017
This study, sponsored by the National Institutes of Health and the Tuberculosis Research Centre and YRG-Care in Chennai, India, will examine how treatment of lymphatic filariasis in HIV-infected patients influences the amount of HIV virus in the blood and the progression of HIV infection to AIDS. Filarial infections are common in Chennai, and it is important to understand whether treatment of filariasis affects the course of HIV disease. The information gained from this study could be used to modify treatments for people both with HIV and filarial infections.
Patients 18 years of age and older who are receiving treatment for HIV infection at the Government Hospital HIV clinic or YRG-Care may be eligible for this study. Two groups of patients will be recruited - patients with both HIV and filarial infections, and patients who have HIV infection alone, without filariasis. Candidates are screened with a medical history and review of medical records, physical examination, and blood and stool tests. Women have a urine pregnancy test.
Within one month of screening, all participants receive a single dose of diethylcarbamazine and albendazole, a drug regimen commonly used to treat filarial infection. Patients are followed closely for the first 2 weeks after treatment to check for side effects. They are then seen at 1, 3, 6 and 12 months after the treatment dose for a physical examination and blood test.
|Condition or disease|
|Filarial Infection HIV Infections|
|Study Type :||Observational|
|Estimated Enrollment :||1000 participants|
|Official Title:||Changes in HIV Viral Load in Patients Undergoing Treatment for Filarial Infection|
|Study Start Date :||August 8, 2005|
|Estimated Study Completion Date :||January 31, 2012|
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00344279
|Government General Hospital|
|Tuberculosis Research Centre|