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ROSCAP: Reduction of Smoking in Cardiac Patients Study

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ClinicalTrials.gov Identifier: NCT00301626
Recruitment Status : Completed
First Posted : March 13, 2006
Last Update Posted : October 24, 2008
Sponsor:
Information provided by:
Minneapolis Veterans Affairs Medical Center

Brief Summary:
Background. The ROSCAP Study was a randomized controlled trial in heart disease patients to test the effect of a smoking reduction intervention on cigarettes per day (cpd) and biochemical and clinical indicators of tobacco exposure. .

Condition or disease Intervention/treatment Phase
Nicotine Dependence Tobacco Dependence Cardiac Disease Behavioral: smoking reduction intervention (including NRT) Not Applicable

Study Type : Interventional  (Clinical Trial)
Enrollment : 180 participants
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)
Study Start Date : October 2000
Study Completion Date : January 2005

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Smoking




Primary Outcome Measures :
  1. Smoking reduction

Secondary Outcome Measures :
  1. Smoking cessation, biomarker measures


Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years to 80 Years   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • smoked at least 15 cigarettes per day and had one of 11 cardiovascular disorders: history of myocardial infarction, coronary artery bypass surgery, angioplasty, stent placement, thrombolytic therapy, angina, arrhythmia, a history of cardiac arrest, greater than 50% coronary artery stenosis by angiography, ischemia on exercise tolerance testing or congestive heart failure, required to confirm that they were unwilling or uninterested in setting a stop smoking date in the next 30 days.

Exclusion Criteria:

  • 1) unstable angina within the past 2 weeks, 2) unstable psychiatric or substance use disorders or 3) contraindications to nicotine replacement therapy (including pregnancy or intention to become pregnant)

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00301626


Locations
United States, Minnesota
Minneapolis VAMC (111-0)
Minneapolis, Minnesota, United States, 55417
Sponsors and Collaborators
National Institutes of Health (NIH)
Investigators
Principal Investigator: Anne Joseph, MD, MPH Minneapolis VAMC & University of Minnesota

ClinicalTrials.gov Identifier: NCT00301626     History of Changes
Other Study ID Numbers: DA13333-02
First Posted: March 13, 2006    Key Record Dates
Last Update Posted: October 24, 2008
Last Verified: April 2005

Keywords provided by Minneapolis Veterans Affairs Medical Center:
tobacco
nicotine
smoking reduction

Additional relevant MeSH terms:
Tobacco Use Disorder
Heart Diseases
Substance-Related Disorders
Chemically-Induced Disorders
Mental Disorders
Cardiovascular Diseases