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ROSCAP: Reduction of Smoking in Cardiac Patients Study

This study has been completed.
Sponsor:
ClinicalTrials.gov Identifier:
NCT00301626
First Posted: March 13, 2006
Last Update Posted: October 24, 2008
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by:
Minneapolis Veterans Affairs Medical Center
  Purpose
Background. The ROSCAP Study was a randomized controlled trial in heart disease patients to test the effect of a smoking reduction intervention on cigarettes per day (cpd) and biochemical and clinical indicators of tobacco exposure. .

Condition Intervention
Nicotine Dependence Tobacco Dependence Cardiac Disease Behavioral: smoking reduction intervention (including NRT)

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)

Resource links provided by NLM:


Further study details as provided by Minneapolis Veterans Affairs Medical Center:

Primary Outcome Measures:
  • Smoking reduction

Secondary Outcome Measures:
  • Smoking cessation, biomarker measures

Estimated Enrollment: 180
Study Start Date: October 2000
Estimated Study Completion Date: January 2005
  Eligibility

Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.


Ages Eligible for Study:   18 Years to 80 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • smoked at least 15 cigarettes per day and had one of 11 cardiovascular disorders: history of myocardial infarction, coronary artery bypass surgery, angioplasty, stent placement, thrombolytic therapy, angina, arrhythmia, a history of cardiac arrest, greater than 50% coronary artery stenosis by angiography, ischemia on exercise tolerance testing or congestive heart failure, required to confirm that they were unwilling or uninterested in setting a stop smoking date in the next 30 days.

Exclusion Criteria:

  • 1) unstable angina within the past 2 weeks, 2) unstable psychiatric or substance use disorders or 3) contraindications to nicotine replacement therapy (including pregnancy or intention to become pregnant)
  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00301626


Locations
United States, Minnesota
Minneapolis VAMC (111-0)
Minneapolis, Minnesota, United States, 55417
Sponsors and Collaborators
National Institutes of Health (NIH)
Investigators
Principal Investigator: Anne Joseph, MD, MPH Minneapolis VAMC & University of Minnesota
  More Information

ClinicalTrials.gov Identifier: NCT00301626     History of Changes
Other Study ID Numbers: DA13333-02
First Submitted: March 10, 2006
First Posted: March 13, 2006
Last Update Posted: October 24, 2008
Last Verified: April 2005

Keywords provided by Minneapolis Veterans Affairs Medical Center:
tobacco
nicotine
smoking reduction

Additional relevant MeSH terms:
Tobacco Use Disorder
Heart Diseases
Substance-Related Disorders
Chemically-Induced Disorders
Mental Disorders
Cardiovascular Diseases