Modelling Internal Hepatic Movement With an External Abdominal Marker
Recruitment status was Recruiting
This study tests the feasibility and reproducibility of patient-specific motion models. These will be used for quantification of safe margin reduction. Patient-specific motion models will be built by post-processing 4D MRI data with non-rigid registration. By comparing these models between visits, model reproducibility will be assessed, and the methodology refined.
Patients With Liver Metastases From Colorectal Cancer
|Study Design:||Time Perspective: Prospective|
|Official Title:||Modelling Internal Hepatic Movement With an External Abdominal Marker Block for Use With a Real Time Position Monitoring System for Respiratory Gating|
|Study Start Date:||June 2006|
The study will use a real time position management (RPM) system for respiratory gating. The RPM system senses the respiration motion of the patient by tracking a pair of reflective markers on a lightweight "marker block" constructed of a synthetic material. This block is placed on the patient's abdomen.
During Radiotherapy, the beam is only switched on at pre-determined phases of respiration. The appropriate phase of respiration is determined by the RPM system. This implies a reliable correlation of external block motion to internal hepatic movement. This correlation is not a simple one, and requires "modeling".
Please refer to this study by its ClinicalTrials.gov identifier: NCT00299299
|Royal Marsden Hospital||Recruiting|
|Chelsea, United Kingdom|
|Contact: Diana Tait 02086613370|
|Principal Investigator: Diana Tait|
|Principal Investigator:||Dr Diana Tait||Royal Marsden HNHS Foundation Trust|