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An Intervention to Reduce Inappropriate Prescriptions of Antibiotics for Respiratory Infections in General Practice

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ClinicalTrials.gov Identifier: NCT00272155
Recruitment Status : Completed
First Posted : January 4, 2006
Last Update Posted : April 27, 2010
Sponsor:
Information provided by:
University of Oslo

Study Description
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Brief Summary:
This study will explore the possible effect of a tailored educational intervention towards general practitioners, in order to improve antibiotic prescriptions for respiratory infections.

Condition or disease Intervention/treatment Phase
Respiratory Tract Infections Anti-Bacterial Agents Behavioral: Educational intervention Behavioral: Educational intervention program Phase 1 Phase 2

Study Design
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Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 118621 participants
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)
Primary Purpose: Health Services Research
Official Title: Can Antibiotic Prescriptions in Respiratory Tract Infections be Improved? A Cluster Randomized Educational Intervention in General Practice
Study Start Date : January 2006
Actual Primary Completion Date : March 2007
Actual Study Completion Date : March 2007

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Antibiotics

Arms and Interventions
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Intervention Details:
  • Behavioral: Educational intervention
    Educational outreach visits to the CME-groups, work-shops, audit and feedback
  • Behavioral: Educational intervention program
    The 433 recruited GPs had a total of 1336 717 office consultations of which 171 679 (12.8%) were RTIs encounters for 118 621 different patients. The GPs participated in peer continuing medical education (CME) groups in southern Norway. A multifaceted intervention was tailored, where key components were educational outreach visits to the CME-groups, work-shops, audit and feedback. Prescription Peer Academic Detailers conducted the educational outreach visits. During these visits, evidence-based recommendations of antibiotic prescriptions for RTIs were presented and software handed out for installation in participants PCs, enabling collection of prescription data. These data was linked to corresponding data from the Norwegian Prescription Database (NorPD). Main outcomes are baseline proportion of inappropriate antibiotic prescriptions for RTIs and change in prescription patterns compared to baseline one year after the initiation of the tailored pedagogic intervention.

Outcome Measures
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Primary Outcome Measures :
  1. Change in antibiotic prescription patterns for respiratory infections [ Time Frame: 1 year ]
    From the 1.336.717 office consultations, main outcomes data (baseline proportion of inappropriate antibiotic prescriptions for RTIs and change in prescription patterns compared to baseline) was measured 1 year after the initiation of the tailored pedagogic intervention.


Eligibility Criteria
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Ages Eligible for Study:   Child, Adult, Older Adult
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • General practitioner
  • Specialist in general practice
Contacts and Locations
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To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00272155


Locations
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Norway
University of Oslo
Oslo, Norway
Sponsors and Collaborators
University of Oslo
Investigators
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Principal Investigator: Svein Gjelstad, MD University of Oslo
More Information
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Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):

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Responsible Party: Jorund Straand, Professor Md PhD, University of Oslo
ClinicalTrials.gov Identifier: NCT00272155    
Other Study ID Numbers: 850657
First Posted: January 4, 2006    Key Record Dates
Last Update Posted: April 27, 2010
Last Verified: December 2005
Additional relevant MeSH terms:
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Infection
Communicable Diseases
Respiratory Tract Infections
Respiratory Tract Diseases