Efficacy of Pancrelipase on Postprandial Belching and Bloating.
The hypothesis of this study is that the administration of pancrelipase with meals will benefit symptoms of post-prandial bloating, pain and eructation.
Drug: Pancrelipase (Creon) 2 tablets with each meal
|Study Design:||Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Crossover Assignment
Primary Purpose: Treatment
- Abdominal bloating
- Abdominal pain
|Study Start Date:||January 2000|
|Estimated Study Completion Date:||October 2000|
Subjects will complete a double-blind crossover study in which, for one week periods, they will receive two pancrelipase tablets with each of the three major meals or a similarly administered identical placebo. Three times daily, subjects will rate the severity of belching, epigastric discomfort, epigastric fullness, bloating, and nausea.
Please refer to this study by its ClinicalTrials.gov identifier: NCT00266721
|United States, Minnesota|
|Minneapolis, Minnesota, United States, 55417|
|Principal Investigator:||Michael D Levitt, MD||Minneapolis VAMC|