Comprehensive Screening for Women at High Genetic Risk for Developing Breast Cancer
To screen women who are high risk for breast cancer with breast MRI, mammogram and random periareolar fine needle aspiration.
|Study Design:||Observational Model: Cohort
Time Perspective: Prospective
|Official Title:||Comprehensive Screening for Women at High Genetic Risk for Developing Breast Cancer|
|Study Start Date:||November 2001|
|Study Completion Date:||June 2007|
|Primary Completion Date:||July 2006 (Final data collection date for primary outcome measure)|
General Purpose: The purpose of our protocol is develop a comprehensive screening protocol for women at high risk for developing breast cancer in the hopes of detecting breast cancer or it's precursor lesions at the earliest possible stage and reducing breast cancer mortality.
The following are our specific goals in this endeavor;
- To assess the sensitivity and specificity of MRI in breast cancer detection in women at high risk compared to mammography
- To assess the ability of random periareolar fine needle aspiration to detect abnormal ductal cells and to correlate these results with MRI and mammogram findings
- To assess appropriate screening intervals for BRCA1/2 mutation carriers and women with a >10% risk of developing breast cancer in ten years The following aims will be outlined in detail under methodology.
Please refer to this study by its ClinicalTrials.gov identifier: NCT00255060
|United States, California|
|Stanford University School of Medicine|
|Stanford, California, United States, 94305|
|Principal Investigator:||James M Ford||Stanford University|