Substitution of First Phase Insulin Response in Patient With Type 2 Diabetes.
|ClinicalTrials.gov Identifier: NCT00254085|
Recruitment Status : Unknown
Verified September 2005 by University Hospital, Gentofte, Copenhagen.
Recruitment status was: Recruiting
First Posted : November 15, 2005
Last Update Posted : November 15, 2005
|Condition or disease||Intervention/treatment||Phase|
|Type 2 Diabetes||Drug: Insulin Aspart||Phase 4|
Patients with Type 2 diabtes has a defect in the insulinsecretion combined with an increased insulin resistance. At an intravenously glucosestimulation, patients with Type 2 diabtes has a decresed first phase insulin response compared to healty peoples. Because the hyperglycemia after meal, observed i Type 2 diabetics patients, is related to the defect in the first phase insulin response it is our hypothesis that substitution of the first phase insulin response with a little dose of insulin could normalise the blood glucose after the meal.
20 patients with Type 2 diabetes will in a randomised, placebocontrolled, dobble-dummy study be included for three days treatment with Insulin aspart vs placebo. Primary endpoint is bloodglucose fluctuations monitored by a continously glucose monitor.
|Study Type :||Interventional (Clinical Trial)|
|Estimated Enrollment :||20 participants|
|Intervention Model:||Crossover Assignment|
|Official Title:||Multiple Substitution of First Phase Insulin Response With a Rapid Action Insuli Analogue in Patient With Newly Diagnosed Type 2 Diabtes.|
|Study Start Date :||March 2005|
|Estimated Study Completion Date :||March 2006|
- Blood glucose fluctuations
- number of hypoglycemia
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00254085
|Contact: Charlotte Gredal, MD||+45 39 77 79 email@example.com|
|Gentofte University Hospital||Recruiting|
|Hellerup, Denmark, 2900|
|Contact: Charlotte Gredal, MD +45 39 77 79 76 firstname.lastname@example.org|
|Principal Investigator: Charlotte Gredal, MD|
|Principal Investigator:||Charlotte Gredal, MD||Gentofte University Hospital|