We updated the design of this site on December 18, 2017. Learn more.
ClinicalTrials.gov
ClinicalTrials.gov Menu

Study of Follicle Stimulating Hormone (FSH) Receptor in Women With Low Antral Follicle Count

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
ClinicalTrials.gov Identifier: NCT00231504
Recruitment Status : Completed
First Posted : October 4, 2005
Last Update Posted : January 6, 2010
Sponsor:
Information provided by:
Assistance Publique - Hôpitaux de Paris

Brief Summary:

The deficit in the total number of antral follicles is associated with a reduction of the ovarian fertility potential in young women.

The principal objective of this study is to evaluate the relationship between FSH receptor polymorphism and antral follicle count.

The investigators have designed a study of FSH receptor polymorphisms P1 and P2 as an association with a low antral follicle count in the ovary.


Condition or disease Intervention/treatment Phase
Antral Follicle Deficit Fertility Procedure: Blood samples Phase 1

Detailed Description:
The present study will compare the prevalence of FSH receptor polymorphisms P1 and P2 in women having reduced follicle count (1 to 9 antral follicles) or normal follicle count (13 to 20 antral follicles) determined by ultrasound scans.

Study Type : Observational
Actual Enrollment : 82 participants
Observational Model: Cohort
Time Perspective: Prospective
Official Title: Study of Follicle Stimulating Hormone (FSH) Receptor in Women With Low Antral Follicle Count
Study Start Date : October 2005
Primary Completion Date : March 2009
Study Completion Date : May 2009

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Hormones
U.S. FDA Resources


Intervention Details:
    Procedure: Blood samples
    Blood samples


Biospecimen Retention:   Samples With DNA
DNA


Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.


Ages Eligible for Study:   18 Years to 35 Years   (Adult)
Sexes Eligible for Study:   Female
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
YOUNG WOMAN
Criteria

Inclusion Criteria:

  • 18 to 35 years old
  • 1 to 9 or 13 to 20 antral follicles
  • Caucasian, occidental Europe
  • Presence of both ovaries
  • Informed consent

Exclusion Criteria:

  • Ovarian anomalies
  • Menopause
  • Pregnancy
  • Other diseases

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00231504


Locations
France
Antoine Beclere Hospital, Obstetrics and Gynaecology and Reproduction Medicine Service
Paris, France, 92140
Sponsors and Collaborators
Assistance Publique - Hôpitaux de Paris
Investigators
Principal Investigator: Renato FANCHIN, MD Assistance Publique - Hôpitaux de Paris

Responsible Party: Christophe Aucan, Department Clinical Rechearch of Developpement
ClinicalTrials.gov Identifier: NCT00231504     History of Changes
Other Study ID Numbers: P041013
CRC04140
First Posted: October 4, 2005    Key Record Dates
Last Update Posted: January 6, 2010
Last Verified: March 2007

Keywords provided by Assistance Publique - Hôpitaux de Paris:
Polymorphism P1
Polymorphism P2
FSH Receptor
Antral follicle count
FSH receptor polymorphism

Additional relevant MeSH terms:
Hormones
Follicle Stimulating Hormone
Hormones, Hormone Substitutes, and Hormone Antagonists
Physiological Effects of Drugs